Retinal Degenerative Diseases and Experimental Therapy
Springer-Verlag New York Inc.
978-1-4757-7224-1 (ISBN)
Specific Gene Defects Cause Photoreceptor Degeneration.- Evidence for Myosin VIIa-Driven Transport of Rhodopsin in the Plasma Membrane of the Photoreceptor-Connecting Cilium.- Blindness in Usher Syndrome 1B.- Different Mutations in RPE65 Are Associated with Variability in the Severity of Retinal Dystrophy.- The RPE65-Deficient Mouse as a Model for RPE65-Associated Leber’s Congenital Amaurosis and Related Disorders.- CRALBP and Inherited Retinal Degeneration.- Guanylyl Cyclase Genes and Their Role in Retinal Degeneration.- Loss of Cone and Reduction in Rod ERG Responses in the Guanylyl Cyclase-E (GC-E) Deficient Mouse.- Guanylyl Cyclase Gene is the Disease Locus in the rd Chicken.- Leber’s Congenital Amaurosis.- Retinal Degeneration is Accelerated when a Mutant Rhodopsin Transgene is Expressed on a Haploid or Null Rhodopsin Background.- Rhodopsin C-Terminal Sequence Qvs(A)Pa Directs Its Sorting To The Ros In Retinal Photoreceptors.- The Cytoplasmic Tail of Rhodopsin Acts as a Sorting Signal in Polarized Photoreceptors and MDCK Cells.- A Homozygous 1-Base Pair Deletion (1147dela) in the Arrestin Gene in Autosomal Recessive Retinitis Pigmentosa.- mRNA Analysis of Oguchi Patients with the Frequent 1147delA Mutation in the Arrestin Gene.- Mutation Spectrum in the Rep-1 Gene of Japanese Choroideremia Patients.- Phenotype-Genotype Correlations in Retinal Degenerations Caused by Abcr gene Mutations.- Autosomal Dominant Macular Degeneration Localized to Chromosome 6q by Linkage Analysis.- The Gene Product of IMPG1 is the Glycoprotein SPACR, not an IPM Proteoglycan.- Bardet-Biedl Syndrome.- Genetic Mapping and Evaluation of PDE6A in 49 Spanish Families with Autosomal Recessive Retinitis Pigmentosa.- Grading Device for Light Perception with Retinitis Pigmentosa.- Blue ConeMonochromacy.- The Peripherin/rds Gene.- Autosomal Dominant Retinitis Pigmentosa and Hyperopia.- Intraocular Pressure in Tapetoretinal Degenerations.- Gene Therapy for Photoreceptor Rescue.- Ribozymes Directed Against Messenger RNAs Associated With Autosomal Dominant Retinitis Pigmentosa.- Ribozyme-Mediated Gene Therapy for Autosomal Dominant Retinal Degeneration.- Targeting Müller Cells for Gene Therapy.- The Involvement of Light in Retinal Degeneration.- Dark Adaptation is Impaired in Diabetics before Photopic Visual Losses Can be Seen.- Age and Monocular Enucleation as Potential Determinants of Light Damage in the Mouse Retina.- Ultraviolet Light Damage and Reversal by Retinoic Acid in Juvenile Goldfish Retina.- A Comparison of Light-Induced Rod Degeneration in Two Teleost Models.- Regulation of Light Absorption in the Pigmented Rat Retina.- An Uncoupling Effect of Reactive Oxygen Species on the Retinal Horizontal Cells.- Animal Models with Photoreceptor Degeneration.- Animal Model for Retinitis Pigmentosa.- Development Of Rat Models For Choroidal Neovascularisation (CNV).- Identification of Degeneration-Specific Genes in the Rcs Rat Retina By Subtractive Hybridization Techniques.- Analysis of Field Potentials and Spike Patterns Evoked by Local Electrical Stimulation of the Chicken Retina.- Molecular and Cell Biological Studies.- Antisense Inactivation of Rds/Peripherin in Xenopus Laevis Embryonic Retinal Cultures.- Phosducin-Like Protein 1 (Phlp1) and Phosducin-Like Orphan Protein 1 (Phlop1).- Organization of The Interphotoreceptor Matrix.- Diverse Localization of Cyclic Nucleotide Gated Channels in the Outer Segments of Rods and Cones.- Retinal Prosthesis as a Replacement for Photoreceptors.- Development of an Epiretinal Electronic Visual Prosthesis.- ResponseCharacteristics of Subretinal Microphotodiode-Based Implant-Mediated Cortical Potentials.- Electrical Stimulation of the Human Retina.- Goals,Concepts,and Current State of the Retina Implant Project.- Are Subretinal Microphotodiodes Suitable as a Replacement For Degenerated Photoreceptors?.- Neuroprotective Agents Romote Photoreceptor Survival.- Rods Produce a Diffusible Factor Promoting Cone Photoreceptor Survival In Vivo and in Vitro.- Pigment Epithelium-Derived Factor (PEDF) in the Retina.- Retinal Neurons in Primary Cell Culture.- Melatonin Receptor Blockers Enhance Photoreceptor Survival and Function in Light Damaged Rat Retina.- Transplantation Studies.- IRIS Pigment Epithelial Cell Transplantation in Monkey Eyes.- The Retinal Pigment Epithelial Cell Differentiation and Cell Marker Expression Following Cryopreservation at -80°C and under Liquid Nitrogen at -196°C.
Zusatzinfo | 8 Illustrations, color; 324 Illustrations, black and white; XV, 587 p. 332 illus., 8 illus. in color. |
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Verlagsort | New York, NY |
Sprache | englisch |
Maße | 178 x 254 mm |
Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Augenheilkunde |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie | |
Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie | |
Studium ► 2. Studienabschnitt (Klinik) ► Humangenetik | |
Technik ► Medizintechnik | |
ISBN-10 | 1-4757-7224-6 / 1475772246 |
ISBN-13 | 978-1-4757-7224-1 / 9781475772241 |
Zustand | Neuware |
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