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Advances in Drug Discovery Techniques -

Advances in Drug Discovery Techniques

Alan L. Harvey (Herausgeber)

Buch | Hardcover
224 Seiten
1998
John Wiley & Sons Inc (Verlag)
978-0-471-97509-0 (ISBN)
CHF 379,95 inkl. MwSt
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This book provides a guide to the various approaches and relevant techniques of improving the process of discovering the leads that can be developed into new medicines.
This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic approaches to drug discovery. Moreover, chapters also focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. Typical screening studies and their link to robotics and informatics are also presented in detail, together with an overview of current progress within antisense therapeutics. Overall, this book will be an excellent reference source for all individuals interested in making sense of the rapid changes in drug discovery that result from developments in molecular biology, robotics and informatics.

Alan L. Harvey is the author of Advances in Drug Discovery Techniques, published by Wiley.

Sense, Nonsense and Antisense: Different Approaches to Drug Discovery (A. Harvey).

Natural Products for Durg Discovery: An Overview (P. Waterman).

Advanced Screening Technology and Informatics for Natural Products Drug Discovery (D. Hill).

Discovery of Specific Tyrosine Kinase Inhibitors from Microbial and Botanical Sources (G. McMahon, et al.).

Plant Cell Culture: A Vehicle for Drug Discovery (A. Stafford, et al.).

Pharmacy of the Deep -
Marine Organisms as Sources of Anticancer Agents (M. Jaspars).

Drug Discovery by Using Molecular Biology to Reprogramme Microorganisms (I. Hunter).

Small Molecule Drug Screening Based on Surface Plasmon Resonance (S. Kumar & K. Gunnarsson).

An Overview of Combinatorial Chemistry and Its Applications to the Identification of Matric Metalloproteinase Inhibitors (MMPIs) (S. Shuttleworth).

New Methods for Structure-based De Novo Drug Design (B. Waszkowycz).

Current and Future Capabilities in Automated Drug Screening and Development (I. Norrington).

Antisense Oligonucleotide Therapeutics (C. Bennett, et al.).

Index.

Erscheint lt. Verlag 15.8.1998
Verlagsort New York
Sprache englisch
Maße 153 x 238 mm
Gewicht 454 g
Einbandart gebunden
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Pharmazie
Naturwissenschaften Chemie
Technik
ISBN-10 0-471-97509-5 / 0471975095
ISBN-13 978-0-471-97509-0 / 9780471975090
Zustand Neuware
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