Introduction to Modern Liquid Chromatography (eBook)

Lloyd R. Snyder, Joseph J. Kirkland, John W. Dolan (Autoren)

eBook Download: PDF | EPUB

2011 | 3. Auflage
960 Seiten
John Wiley & Sons (Verlag)
978-1-118-21039-0 (ISBN)

Infos

The latest edition of the authoritative reference to HPLC

High-performance liquid chromatography (HPLC) is today the
leading technique for chemical analysis and related applications,
with an ability to separate, analyze, and/or purify virtually any
sample. Snyder and Kirkland's Introduction to Modern Liquid
Chromatography has long represented the premier reference to
HPLC. This Third Edition, with John Dolan as added coauthor,
addresses important improvements in columns and equipment, as well
as major advances in our understanding of HPLC separation, our
ability to solve problems that were troublesome in the past, and
the application of HPLC for new kinds of samples.

This carefully considered Third Edition maintains the
strengths of the previous edition while significantly modifying its
organization in light of recent research and experience. The text
begins by introducing the reader to HPLC, its use in relation to
other modern separation techniques, and its history, then leads
into such specific topics as:

* The basis of HPLC separation and the general effects of
different experimental conditions

* Equipment and detection

* The column--the "heart" of the HPLC system

* Reversed-phase separation, normal-phase chromatography,
gradient elution, two-dimensional separation, and other
techniques

* Computer simulation, qualitative and quantitative analysis, and
method validation and quality control

* The separation of large molecules, including both biological
and synthetic polymers

* Chiral separations, preparative separations, and sample
preparation

* Systematic development of HPLC separations--new to this
edition

* Troubleshooting tricks, techniques, and case studies for both
equipment and chromatograms

Designed to fulfill the needs of the full range of HPLC users, from
novices to experts, Introduction to Modern Liquid
Chromatography, Third Edition offers the most up-to-date,
comprehensive, and accessible survey of HPLC methods and
applications available.

Autor

Lloyd R. Snyder, PhD, is a Principal at LC Resources in Walnut Creek, California. He is the author or coauthor of several books including An Introduction to Separation Science, Introduction to Modern Liquid Chromatography, Second Edition, the bestselling Practical HPLC Method Development, Second Edition, and the comprehensive High-Performance Gradient Elution, all published by Wiley. Joseph J. Kirkland, PhD, is Vice President of Research and Development for Advanced Materials Technology, Inc., and coauthor of Introduction to Modern Liquid Chromatography, Second Edition, Practical HPLC Method Development, Second Edition, and Modern Size-Exclusion Liquid Chromatography, Second Edition, all published by Wiley. John W. Dolan, PhD, is a Principal at LC Resources. He is author of the popular "LC Troubleshooting" column in LCGC magazine and coauthor with Lloyd Snyder of Troubleshooting LC Systems and High-Performance Gradient Elution.

Rezensionen

"In summary, I would strongly recommend this book for anyone
working with LC and LC/MS. It is a finely crafted introduction that
adequately covers nearly every aspect of the science. The emphasis
on basic principles and practical aspects ensures that it will be a
useful reference for many years to come." (J Am Soc Mass Spectrom,
2011)

"This third edition is highly cross-referenced, so as to allow
the reader to follow up on topics of special interest, or to
clarify questions that may arise during reading. The third edition
of Introduction to Modern Liquid Chromatography will continue to be
the HPLC reference book for thousands of readers, either
experienced workers who may wish to explore topics of his/her
choice, or find an answer to specific problems, or beginners who
would like to understand and know the possibilities offered by
the

technique." (Chemistry Journals, 11 April 2011)

"This classic text on liquid chromatography has been thoroughly
updated through the addition of information on modern
instrumentation, columns, and troubleshooting. It is a valuable
resource for practicing chromatographers at all levels.." (Anal
Bioanal Chem, 2011)

"In summary, I would strongly recommend this book for anyone
working with LC and LC/MS. It is a finely crafted introduction that
adequately covers nearly every aspect of the science. The emphasis
on basic principles and practical aspects ensures that it will be a
useful reference for any years to come." (American Society for Mass
Spectrometry, 21 Januay 2011)

"The text is illustrated with many figures and tables
originating from authors' own work or taken from the literature . .
. both groups of readers will find in this book plenty of
information and inspiration." (Journal of Separation Science, 1
June 2010)

"Following their highly successful second edition (1979), which
appeared more than 30 years ago, Snyder (LC Resources) and Kirkland
(Advanced Materials Technology) have teamed with Dolan (LC
Resources) and additional collaborators to provide an excellent
update of their earlier work." (CHOICE, July 2010)

"It is difficult in these times to ever call a scientific book a
"bargain", but this truly is. The wealth of information contained
in these almost 1000 pages is invaluable. The book is
comprehensive, eminently readable and approachable, and highly
useful for both the skilled chromatographer and those new to the
technique. Everyone using a liquid chromatographic instrument would
benefit from owning a copy." (JACS, 2010)

"It's current, clearly-indexed, well-referenced, and
comprehensive. The inclusion of John Dolan as author has
significantly expanded the sections on troubleshooting, and
additional expert contributors have enhanced the coverage of the
specialist chapters." - Bruce Hamilton posted on the Chromatography
Forum

Produkt-Details

• Erscheint lt. Verlag: 20.9.2011
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Chemie ► Analytische Chemie
• Themenwelt: Technik
• Schlagworte: Analytical Chemistry • Analytische Chemie • Biowissenschaften • Cell & Molecular Biology • Chemie • Chemistry • Drug Discovery & Development • Flüssigkeitschromatographie • Flüssigkeitschromatographie • Life Sciences • Wirkstoffforschung u. -entwicklung • Zell- u. Molekularbiologie
• ISBN-10: 1-118-21039-5 / 1118210395
• ISBN-13: 978-1-118-21039-0 / 9781118210390