The Ubiquitous Roles of Cytochrome P450 Proteins, Volume 3 (eBook)

Astrid Sigel, Helmut Sigel, Roland K. O. Sigel (Herausgeber)

eBook Download: PDF

2007 | 1. Auflage
678 Seiten
John Wiley & Sons (Verlag)
978-0-470-02814-8 (ISBN)

Infos

Helmut Sigel, Astrid Sigel and Roland K.O. Sigel, in close
cooperation with John Wiley & Sons launch a new Series
"Metal Ions in Life Sciences".

There exists a whole range of books on Cytochromes P450, but
none with the focus of this volume. This new volume in the Series
concentrates on current hot topics in the area and tries to work
out the underlying common developments.

As a result the reader will find a systematic account of new
results in this exciting research area. The table of contents
gives an idea on the wide span of chapters, starting with overviews
and the presentation of specific systems, and ending with
chapters on carbon-carbon bond cleavage by P450 sytems, drug
metabolism as catalyzed by P450 systems, decomposition of
xenobiotics by P450 enzymes and design and engineering of new P450
systems.

Autor

Astrid Sigel has studied languages and was an editor of the Metal Ions in Biological Systems series (until Volume 44) and also of the Handbooks on Toxicity of Inorganic Compounds (1988), on Metals in Clinical and Analytical Chemistry (1994; both with H.G. Seiler), and on Metalloproteins (2001; with Ivano Bertini) (Dekker, New York). Helmut Sigel is Emeritus Professor (2003) of Inorganic Chemistry at the University of Basel, Switzerland, and a previous editor of the MIBS series until Volume 44. He serves on various editorial and advisory boards, published over 300 articles on metal ion complexes of nucleotides, coenzymes, and other ligands of biological relevance, and lectured worldwide. He was named Protagonist in Chemistry (2002) by ICA (issue 339); among further honors are the P. Ray Award (Indian Chemical Society, of which he is also an Honorary Fellow), the Werner Award (Swiss Chemical Society), a Doctor of Science honoris causa degree (Kalyani University, India), appointments as Visiting Professor (e.g., Austria, China, UK) and Endowed Lectureships. Roland K.O. Sigel is Assistant Professor (2003) of Inorganic Chemistry at the University of Zürich, Switzerland, endowed with a Förderungsprofessur of the Swiss National Science Foundation. He received his doctoral degree summa cum laude (1999) from the University of Dortmund, Germany, working with Bernhard Lippert; thereafter he spent nearly three years at Columbia University, New York, USA, in the group of Anna Marie Pyle (now Yale University); during the six years abroad he received several fellowships from various sources. His research focuses on the structural and catalytic role of metal ions in ribozymes, especially group II introns, and on related topics. He was also an editor of Volumes 43 and 44 of the MIBS series.

Rezensionen

"This collective volume is extremely rich, as rich as the chemistry
of P450 enzymes. It shows the vast field, its many facts and
unresolved issues. It will be highly interesting primarily to the
P540 community, medicinal chemists, and biochemists."
(Coordination Chemistry Reviews, February 2009)

"Cytochrome P450 aficionados will not want to be without either
of these two books." (Journal of the American Chemical
Society, December 26, 2007)

"This is a well produced and comprehensive effort." (Doody's
Health Services)

Produkt-Details

• Erscheint lt. Verlag: 30.4.2007
• Reihe/Serie: Metal Ions in Life Sciences
• Reihe/Serie: Metal Ions in Life Sciences
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Chemie ► Anorganische Chemie
• Themenwelt: Technik
• Schlagworte: Bioanorganische Chemie • Biochemie u. Chemische Biologie • Biochemistry (Chemical Biology) • bioinorganic chemistry • Chemie • Chemistry
• ISBN-10: 0-470-02814-9 / 0470028149
• ISBN-13: 978-0-470-02814-8 / 9780470028148