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Uses of Inorganic Chemistry in Medicine -

Uses of Inorganic Chemistry in Medicine

Nicholas P Farrell (Herausgeber)

Buch | Hardcover
172 Seiten
1999
Royal Society of Chemistry (Verlag)
978-0-85404-444-3 (ISBN)
CHF 119,95 inkl. MwSt
This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will be an invaluable asset for many in the discipline.
Metal-based drugs are a commercially important sector of the pharmaceutical business, yet most bioinorganic textbooks lack the space to cover comprehensively the subject of metals in medicine. Uses of Inorganic Chemistry in Medicine approaches an understanding of the topic in a didactic and systematic manner. The field of inorganic chemistry in medicine may usefully be divided into two main categories - drugs which target metal ions in some form, whether free or protein-bound, and secondly, metal-based drugs where the central metal ion is usually the key feature of the mechanism of action. This latter category can further be subdivided into pharmacodynamic and chemotherapeutic applications, as well as those of imaging. The book summarises the chemical and biological studies on clinically used agents of lithium, gold and platinum, as well as highlighting the research on prospective new drugs, including those based on vanadium and manganese. The coverage allows a clear distinction between pharmacodynamic and therapeutic properties of metal-based drugs and focuses not only on those clinical agents in current use, but also on new drugs and uses. This book serves to fill an important niche, bridging bioinorganic and medicinal chemistry and will undoubtedly be of use to senior undergraduates and postgraduates, as well as being an invaluable asset for teachers and researchers in the discipline.

Uses of Inorganic Chemistry in Medicine, Overview;

Biomedical Uses of Lithium;

Gold Complexes with Anti-Arthritic, Anti-Tumour and Anti-HIV Activity;

Nitric Oxide in Physiology and Medicine;

Therapeutic Aspects of Manganese-Based Superoxide Dismutase Mimics;

Vanadium Compounds as Possible Insulin Modifiers;

Cisplatin-Based Anticancer Agents;

Dinuclear and Trinuclear Platinum Anticancer Agents;

Oxidation Damage by Bleomycin, Adriamycin and Other Cytotoxic Agents that Require Iron or Copper;

Subject Index.

Erscheint lt. Verlag 27.5.1999
Co-Autor J H McNeill, Katherine H Thompson, Lloyd R Kelland, N Birch
Verlagsort Cambridge
Sprache englisch
Maße 156 x 234 mm
Gewicht 929 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Medizin / Pharmazie Physiotherapie / Ergotherapie Orthopädie
Naturwissenschaften Chemie Anorganische Chemie
Technik Medizintechnik
ISBN-10 0-85404-444-2 / 0854044442
ISBN-13 978-0-85404-444-3 / 9780854044443
Zustand Neuware
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