Infection and Autoimmunity (eBook)

Nancy Agmon-Levin, Noel R. Rose, Yehuda Shoenfeld (Herausgeber)

eBook Download: PDF

2004 | 1. Auflage
768 Seiten
Elsevier Science (Verlag)
978-0-08-053465-7 (ISBN)

Infos

Autoimmune diseases are conditions where the immune system attacks the body organs instead of foreign invaders. This book deals with the various mechanisms which infectious agents can trigger autoimmunity such as molecular mimicry, polyclonal activation and others. An overview is given with regard to bacteria, viruses and parasites associated with autoimmunity. There is a summary on classical autoimmune diseases and the infecting agents that can induce them.

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Infection and Autoimmunity encompasses the different mechanisms involved in the infection-autoimmunity association/induction. Special attention is given to heat shock proteins (HSPs) and to transgenic mouse models to better understand infection-induced autoimmunity. Organized into six parts, this book first discusses the mechanisms of autoimmune induction by infection. Some chapters follow discussing the vaccination and vaccines, including the controversial issue of vaccine-autoimmunity relationship. Other chapters elucidate the relationship of bacteria and parasites to autoimmunity. Lastly, the aspects of infections and diseases are described. This reference material will help readers gain a deeper insight into the important etiological aspects of autoimmunity. - The only book directed at the interactions between infectious agents and autoimmunity- Describes the prevalence and incidence of the global issues and current therapeutic approaches- Presents the measures for infection control- Completely updated, with new chapters- One-stop reference with easy access to topics

Inhalt

Front Cover 1
Infection and Autoimmunity 4
Copyright Page 5
Contents 18
List of Contributors 8
Introduction: Infection and Autoimmunity 22
Part I: Mechanisms of Autoimmune Induction by Infection 26
Chapter 1. Implications of T Cell Receptor Crossreactivity for the Pathogenesis of Autoimmune Diseases 28
Chapter 2. Epitope Spreading 40
Chapter 3. Molecular Mimicry in Multiple Sclerosis: Role of MHC-Altered Peptide Ligands (MAPL) 66
Chapter 4. Adverse Events of Desirable Gain in Immunocompetence: The Immune Restoration Inflammatory Syndromes (IRIS) 78
Chapter 5. CD5-Expressing B Cells and Infection 86
Chapter 6. Endothelial Cell Autoreactivity and Infection 96
Part II: Vaccination 106
Chapter 7. Induction of Autoimmunity by Adjuvant Hydrocarbons 108
Chapter 8. Vaccination and Autoimmunity 126
Chapter 9. BCG Vaccination 138
Part III: Viruses 142
Chapter 10. Viruses: The Culprits of Autoimmune Diseases? 144
Chapter 11. How Transgenic Mouse Models Contribute to a Better Understanding of Virus-Induced Autoimmunity 176
Chapter 12. Epstein-Barr Virus and Autoimmunity 184
Chapter 13. HIV and Autoimmunity 192
Chapter 14. Parvovirus B19 Infection and its Association to Autoimmune Disease 202
Chapter 15. Hepatitis C Infection and Vasculitis 210
Chapter 16. HCV and Cryoglobulinemia 222
Chapter 17. Virus-induced Systemic Vasculitides 234
Chapter 18. Viral Infections and Autoimmune Hepatitis 242
Chapter 19. Viral Infections and Type 1 Diabetes 250
Chapter 20. Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease (TMEV-IDD) and Autoimmunity 272
Chapter 21. Viruses and Multiple Sclerosis 284
Chapter 22. Endogenous Retroviruses as Etiological Agents in Systemic Lupus Erythematosus 292
Chapter 23. Sjögren's Syndrome – Autoimmune Epithelitis: Role of Coxsackieviruses in Pathogenesis 310
Chapter 24. Viral Infection and Heart Disease: Autoimmune Mechanisms 320
Part IV: Bacteria and Autoimmunity 340
Chapter 25. Rheumatic Fever: How Streptococcal Throat Infection Triggers an Autoimmune Disease 342
Chapter 26. Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) 354
Chapter 27. Helicobacter Pylori Infection and Gastric Autoimmunity: Coincidence or Cause–Effect Relationship? 366
Chapter 28. Yersinia Enterocolitica Infections and Autoimmune Thyroid Diseases 384
Chapter 29. Reactive Arthritis (Reiter's Syndrome): Roles of Infection, HLA-B27 and the Immune Response 394
Chapter 30. Bovine Spongiform Encephalopathy as an Autoimmune Disease Evoked by Acinetobacter: Implications for Multiple Sclerosis and Creutzfeldt–Jakob Disease 404
Chapter 31. Infection and Autoimmunity in Patients with Antibiotic Treatment-Resistant Lyme Arthritis 416
Chapter 32. Post-Infectious Arthritis: Reactive Arthritis or Slow Infectious Arthritis? 424
Part V: Parasites and Autoimmunity 458
Chapter 33. Parasitic Infection and Autoimmunity 460
Chapter 34. Autoimmunity in Chagas' Disease 470
Chapter 35. Anti-Saccharomyces Cerevisiae Antibodies and Autoimmune Diseases 488
Part VI: Infection and Diseases 492
Chapter 36. The Infectious Origin of the Antiphospholipid Syndrome 494
Chapter 37. SLE and Infections 512
Chapter 38. Type I Diabetes Mellitus, Infection and Toll-like Receptors 526
Chapter 39. Infection and Autoimmune Thyroid Diseases 536
Chapter 40. Pemphigus and Infection 552
Chapter 41. Infection, Autoimmunity and Autoimmune Liver Diseases 558
Chapter 42. Infections and Vasculitis 570
Chapter 43. Infection and Multiple Sclerosis 580
Chapter 44. Infections and Polymyositis–Dermatomyositis 604
Chapter 45. Infection and Guillain-Barré Syndrome 612
Chapter 46. Infection and Systemic Sclerosis 634
Chapter 47. Tuberculosis and SLE-like Symptoms as a Complication of Biological Anti-TNF Therapy 644
Chapter 48. Infection and Behçet's Syndrome 650
Chapter 49. Infections and Immune Thrombocytopenic Purpura 658
Chapter 50. Inflammatory Bowel Disease 670
Chapter 51. Infection and Spondyloarthropathies 696
Chapter 52. Celiac Disease and Infection 708
Chapter 53. Infections Associated with Retinal Autoimmunity 712
Chapter 54. Infection and Atherosclerosis 722
Chapter 55. The Pathogenic Role of Heat Shock Proteins in Atherosclerosis 732
Chapter 56. Interaction between Rheumatoid Arthritis and Infections 750
Subject Index 762

Produkt-Details

• Erscheint lt. Verlag: 18.9.2004
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Technik
• ISBN-10: 0-08-053465-1 / 0080534651
• ISBN-13: 978-0-08-053465-7 / 9780080534657