Viruses and Human Disease (eBook)

Ellen G. Strauss, James H. Strauss (Autoren)

eBook Download: EPUB

2007 | 2. Auflage
480 Seiten
Elsevier Science (Verlag)
978-0-08-055316-0 (ISBN)

Infos

Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss' virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease.
* Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information
* Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia.
* Further reading sections at the end of each chapter make it easy find key references
* World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text
* A companion website features illustrations for use in class notes and presentations.

Inhalt

Front Cover 1
Viruses and Human Disease 4
Copyright Page 5
Table of Contents 6
Preface to the Second Edition 8
Chapter 1: Overview of Viruses and Virus Infection 9
Introduction 9
Classification of Viruses 14
An Overview of the Replication Cycle of Viruses 15
Effects of Virus Infection on the Host Cell 37
Epidemiology: The Spread of Viruses from Person to Person 39
Further Reading 40
Chapter 2: The Structure of Viruses 43
Introduction 43
Helical Symmetry 43
Icosahedral Symmetry 44
Nonenveloped Viruses with More Complicated Structural Features 53
Enveloped Viruses 53
Assembly of Virions 66
Stability of Virions 69
Further Reading 70
Chapter 3: Plus-Strand RNA Viruses 71
Introduction 71
Family Picornaviridae 71
Family Caliciviridae 91
Family Hepeviridae 94
Family Astroviridae 95
Family Togaviridae 97
Family Flaviviridae 114
Family Coronaviridae 132
Family Arteriviridae 136
Family Roniviridae 138
The Plus-Strand RNA Viruses of Plants 138
Origin and Evolution of Plus-Strand RNA Viruses 140
Further Reading 142
Chapter 4: Minus-Strand RNA Viruses 145
Introduction 145
Overview of the Minus-Strand RNA Viruses 145
Family Rhabdoviridae 149
Family Paramyxoviridae 155
Family Filoviridae 166
Family Bornaviridae 169
Family Orthomyxoviridae 170
Family Bunyaviridae 183
Family Arenaviridae 191
Evolution of Minus-Strand RNA Viruses 196
Further Reading 197
Chapter 5: Viruses That Contain Double-Stranded RNA: Family Reoviridae 201
Introduction 201
Overview of the Family Reoviridae 201
Further Reading 217
Chapter 6: Viruses Whose Life Cycle Uses Reverse Transcriptase 219
Introduction 219
Family Retroviridae 220
Family Hepadnaviridae 257
Further Reading 266
Chapter 7: DNA-Containing Viruses 269
Introduction 269
Family Poxviridae 271
Family Herpesviridae 284
Replication of Herpesviruses 290
Family Adenoviridae 303
Family Polyomaviridae 310
Family Papillomaviridae 316
Family Parvoviridae 322
Torque Teno Virus: A Newly Described Human Virus 328
Further Reading 330
Chapter 8: Emerging and Reemerging Viral Diseases 333
Bat-Associated Viruses 333
Viruses Associated with Birds 339
Viruses Associated with Primates 344
Viruses Associated with Rodents 349
Further Reading 350
Chapter 9: Subviral Agents 353
Introduction 353
Defective Interfering Viruses 353
Satellites and Satellite Viruses 356
Viroids and Virusoids 357
Hepatitis delta 358
Prions and Prion Diseases 365
Prions of Yeast 375
Further Reading 376
Chapter 10: Host Defenses against Viral Infection and Viral Counterdefenses 377
Introduction 377
Adaptive Immune System 377
Innate Immune System 397
Viral Counterdefenses 413
Interactions of Viruses with their Hosts 426
Further Reading 427
Chapter 11: Gene Therapy 431
Introduction 431
Virus Vector Systems 431
Use of Viruses As Expression Vectors 440
Gene Therapy 445
Further Reading 454
Appendix: References Used for Figures and Tables 457
Index 469

Produkt-Details

• Erscheint lt. Verlag: 21.9.2007
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Allgemeines / Lexika
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete
• Themenwelt: Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
• Themenwelt: Technik
• ISBN-10: 0-08-055316-8 / 0080553168
• ISBN-13: 978-0-08-055316-0 / 9780080553160