Vitamins and Hormones (eBook)

eBook Download: PDF

1996 | 1. Auflage
202 Seiten
Elsevier Science (Verlag)
978-0-08-086649-9 (ISBN)

Infos

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. Now, new discoveries have proved that several of the vitamins function as hormones and many of the substances inferred by the title of the Serial function in signal transduction processes. Accordingly, the Editor-in-Chief has expanded the scope of the serial to reflect this newer understanding of function-structure relationships in cellular communication. The newly modified Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.
Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

Inhalt

Front Cover 1
Vitamins and Hormones: Advances in Research and Applications 4
Copyright Page 5
Contents 8
Preface 12
Chapter 1. Vitamins C and E and LDL Oxidation 14
I. Introduction 14
II. Mechanisms of LDL Oxidation 18
III. Antioxidant Protection of LDL by Vitamin C 22
IV. LDL Oxidation and Vitamin E 27
V. Trials of in Vivo Antioxidant Supplementation 34
VI. Conclusions 39
References 40
Chapter 2. Antioxidant Vitamins and Human Immune Responses 48
I. Introduction 48
II. Free Radicals 49
III. Essential Micronutrients with Antioxidant Activities 49
IV. Immune Functions 50
V. Free Radicals and Immune Cell Function 52
VI. Clinical Examples of the Interactions of Free Radicals, Antioxidants, and Immune Function 55
VII. Conclusions 68
References 69
Chapter 3. Cytokine Regulation of Bone Cell Differentiation 76
I. Introduction 76
II. Osteoblasts 76
III. Osteoclasts 89
IV. Summary 99
References 99
Chapter 4. The Molecular Pharmacology of Ovarian Steroid Receptors 112
I. Introduction 112
II. The Mechanism of Action of Estrogen and Progesterone 114
III. Steroid Hormone Receptor Antagonists 122
IV. Final Comments 133
References 134
Chapter 5. Signal Transduction Pathways Combining Peptide Hormones and Steroidogenesis 142
I. Introduction 142
II. Acute Action of Peptide Hormones on Steroidogenesis 143
III. Chronic Action of Peptide Hormones on Steroidogenesis 147
IV. Conclusions and Future Directions 156
References 158
Chapter 6. The Roles of 14-3-3 Proteins in Signal Transduction 162
I. Introduction 162
II. 14-3-3 Sequence and Structure Analysis 163
III. Regulation of Cellular Processes by 14-3-3 Proteins 166
IV. 14-3-3 Proteins and Protein Kinases 171
V. Roles of 14-3-3 Proteins in Signal Transduction Pathways 179
VI. Conclusions 182
References 183
Chapter 7. Physiological Roles for Parathyroid Hormone-Related Protein: Lessons from Gene Knockout Mice 190
I. Introduction 190
II. Strategy for Generating PTHrP-Negative Mice 192
III. The PTHrP-Negative Phenotype 194
IV. Summary 203
References 204
Index 208

Produkt-Details

• Erscheint lt. Verlag: 10.12.1996
• Mitarbeit: Chef-Herausgeber: Gerald Litwack
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Gesundheitsfachberufe ► Diätassistenz / Ernährungsberatung
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
• Themenwelt: Medizinische Fachgebiete ► Innere Medizin ► Kardiologie / Angiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Technik
• ISBN-10: 0-08-086649-2 / 0080866492
• ISBN-13: 978-0-08-086649-9 / 9780080866499