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Medical Applications of Colloids (eBook)

Egon Matijevic (Herausgeber)

eBook Download: PDF
2008 | 2008
IX, 319 Seiten
Springer New York (Verlag)
978-0-387-76921-9 (ISBN)

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The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (solid or liquid) in the size range of several nanometers to several micrometers have a tremendous effect on our lives, because they can be bene?cial or detrimental to our well-being. Such particles are present in living bodies as red blood cells or cholesterol crystals in the gall bladder. They are ubiquitous in the environment, where they can cause many diseases, such as asbestosis, silicosis, and black lung disease, but they are also used in diagnostic tests, drug delivery, and numerous other applications. More recently, evidence has become available that drug formulations with active components in a ?nely dispersed state may signi?cantly affect their functionality. Furthermore, with miniaturization of medical instrumentation, the size of the components is necess- ily reduced to colloid or even smaller range. This volume is a collection of several chapters dealing with diverse topics of colloids and surfaces relevant to medical applications. Thus, Siiman describes the use of optical properties of uniform colloidal particles as probes in ?ow cytometry. Giesche focuses on the preparations and properties of exceedingly uniform silica spheres for different uses, such as in chromatography. In modi?ed forms, silica p- ticles with incorporated dyes are employed in diagnostics and those combined with tiny magnetic entities in drug delivery.
The important role of ?nely dispersed matter and surfaces in medicine is not always fully understood and appreciated. Speci?cally, ?ne particles (solid or liquid) in the size range of several nanometers to several micrometers have a tremendous effect on our lives, because they can be bene?cial or detrimental to our well-being. Such particles are present in living bodies as red blood cells or cholesterol crystals in the gall bladder. They are ubiquitous in the environment, where they can cause many diseases, such as asbestosis, silicosis, and black lung disease, but they are also used in diagnostic tests, drug delivery, and numerous other applications. More recently, evidence has become available that drug formulations with active components in a ?nely dispersed state may signi?cantly affect their functionality. Furthermore, with miniaturization of medical instrumentation, the size of the components is necess- ily reduced to colloid or even smaller range. This volume is a collection of several chapters dealing with diverse topics of colloids and surfaces relevant to medical applications. Thus, Siiman describes the use of optical properties of uniform colloidal particles as probes in ?ow cytometry. Giesche focuses on the preparations and properties of exceedingly uniform silica spheres for different uses, such as in chromatography. In modi?ed forms, silica p- ticles with incorporated dyes are employed in diagnostics and those combined with tiny magnetic entities in drug delivery.

Colloids as Light Scattering and Emission Markers for Analysis of Blood.- Medical and Technological Application of Monodispersed Colloidal Silica Particles.- Pharmaceutical Applications of Finely Dispersed Systems.- Transport, Deposition and Removal of Fine Particles - Biomedical Applications.- Medical and Technological Application of Monodispersed Colloidal Silica Particles.

Erscheint lt. Verlag 5.12.2008
Zusatzinfo IX, 319 p.
Verlagsort New York
Sprache englisch
Themenwelt Medizin / Pharmazie
Naturwissenschaften Biologie Genetik / Molekularbiologie
Naturwissenschaften Chemie
Technik Maschinenbau
Technik Medizintechnik
Technik Umwelttechnik / Biotechnologie
Schlagworte Applications • biochemical engineering • Biomaterial • Biomedical Application • Biomedical Applications • Blood • colloid • colloids • Deposition • Diagnostics • Light Scattering • Matijevic • Medical • Pharmaceutical • Surface • Transport
ISBN-10 0-387-76921-8 / 0387769218
ISBN-13 978-0-387-76921-9 / 9780387769219
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