Ganglioside Function

Biochemical and Pharmacological Implications

Buch | Softcover

306 Seiten

2013 | Softcover reprint of the original 1st ed. 1976
Springer-Verlag New York Inc.
978-1-4899-2656-2 (ISBN)

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The volume which is here presented reports all the lectures given at the International Satellite Meeting on Biochemical and Pharmacological Implications of Ganglioside Function held at Cor- tona, Tuscany, Italy from 28 to 31 August, 1975. The Meeting was run just before the 5th International Congress of the International Society for Neurochemistry (Barcelona, 2-7 september, 1975) and was in fact organized on its frame. The general subject matter of gangliosides structure, biosyn- thesis and degradation, of their functional role in neurochemistry, their pharmacological action and future potentialities, was deeply and throughly taken into consideration during the three-day Sympo- sium, which was brilliantly directed and guided by Dr. L. Svenner- holm. The meeting gave certainly, in our opinion, a valuable stimu- lus to research workers interested in the biophysics, chemistry, biochemistry, physiology and pharmacology of gangliosides. The e- ditors wish to express their thanhd to the speakers, the discussants, the Meeting Chairman, the section chairmen and to all the attendants who have taken part at the Symposium and who actively and deeply discussed the delivered lectures.
Our final thank is also for Dr. Francesco della Valle, official representative of FIDIA Research Laboratories, Abano Terme, Padua, Italy, to whom we are grateful for his continuous and efficient support. The contribution of the Secretarial Staffs of both the v PREFACE Department of Biochemistry of Perugia University and FIDIA Labora- tories to the editorial work is also gratefully acknowledged.

Chemistry and Biochemistry of Gangliosides.- Structure and Specificity of Gangliosides.- On a Molecular, Microscale Fingerprinting of Gangliosides.- Biosynthesis of Brain Gangliosides.- Scanning Electron Microscopic and Glycosphingolipid Biosynthetic Studies of Differentiating Mouse Neuroblastoma Cells.- Brain Neuraminidase and Gangliosides.- The Functional Biochemistry of Gangliosides.- Gangliosides of the Neuron: Localization and Origin.- Subcellular Distribution and Possible Role of Gangliosides in the CNS.- Gangliosides and Proteins of Brain Synaptic Components.- Biochemical Evidence on the Role of Gangliosides in Nerve-Endings.- Possible Functional Role of Gangliosides.- Retinal Gangliosides: Composition, Evolution with Age. Biosynthetic and Metabolic Approaches.- Gangliosides and Toxins.- Interaction of Cholera Toxin and Ganglioside GM1.- The Role of Gangliosides in the Action of Cholera Toxin.- The Relationship between the Action of Tetanus Toxin and its Binding by Mem branes and Gangliosides.- Gangliosides in Experimental Pathology and Pharmacology.- History of Recognition Molecules in the Brain, With special reference to the pharmacology of brain gangliosides.- Rat Brain Gangliosides following Drug Addiction and Nutritional Deficiency.- Effects of Brain Gangliosides on Functional Recovery in Experimental Regeneration and Reinnervation.- Participants.

Reihe/Serie	Advances in Experimental Medicine and Biology ; 71
Zusatzinfo	41 Illustrations, black and white; IX, 306 p. 41 illus.
Verlagsort	New York
Sprache	englisch
Maße	155 x 235 mm
Themenwelt	Schulbuch / Wörterbuch
	Geisteswissenschaften
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie ► Biochemie
	Sozialwissenschaften
ISBN-10	1-4899-2656-9 / 1489926569
ISBN-13	978-1-4899-2656-2 / 9781489926562
Zustand	Neuware