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Environmental Toxicology -

Environmental Toxicology (eBook)

T.P. Mommsen, T.W. Moon (Herausgeber)

eBook Download: PDF
2005 | 1. Auflage
560 Seiten
Elsevier Science (Verlag)
978-0-08-045873-1 (ISBN)
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This sixth volume in this established series deals with the biochemical responses of fish to different environmental/ecological factors. Environmental Toxicology captures vital issues affecting the responses of fish to the chemical surroundings of their environment. Chapters included in this volume identify the systems found in fish to deal with xenobiotics, hormonal interactions initiated in the presence of these chemicals, the unique mechanisms used by fish to adjust to the present chemicals, and the new and evolving mixtures of chemicals in their environment. Also included, is a crucial review of the new methods being applied in fish systems to understand the effects of xenobiotics to fish fitness - a key theme in environmental health and critical to the future of fish populations.
* Entirely new topic discussion and most recent volume in the acclaimed series
* Includes chapters detailed on a cellular level
* Introduces discussion of pharmaceutical effects on fish
This sixth volume in this established series deals with the biochemical responses of fish to different environmental/ecological factors. Environmental Toxicology captures vital issues affecting the responses of fish to the chemical surroundings of their environment. Chapters included in this volume identify the systems found in fish to deal with xenobiotics, hormonal interactions initiated in the presence of these chemicals, the unique mechanisms used by fish to adjust to the present chemicals, and the new and evolving mixtures of chemicals in their environment. Also included, is a crucial review of the new methods being applied in fish systems to understand the effects of xenobiotics to fish fitness - a key theme in environmental health and critical to the future of fish populations.* Entirely new topic discussion and most recent volume in the acclaimed series* Includes chapters detailed on a cellular level * Introduces discussion of pharmaceutical effects on fish

Cover 1
Contents 12
Preface 6
Contributors 8
Abbreviations 14
Part 1: General-Models and Techniques 16
Chapter 1. The utility of zebrafish as a model for toxicological research 18
Chapter 2. Use of fish cell lines in the toxicology and ecotoxicology of fish. Piscine cell lines in environmental toxicology 58
Chapter 3. Approaches in proteomics and genomics for eco-toxicology 100
Part 2: Biotransformations/Toxicokinetics 132
Chapter 4. Interactions between lipids and persistent organic pollutants in fish 134
Chapter 5. Metabolic fate of nonylphenols and related phenolic compounds in fish 168
Chapter 6. Pesticide biotransformation in fish 186
Chapter 7. Xenobiotic receptors in fish: Structural and functional diversity and evolutionary insights 206
Part 3: Cellular Changes 244
Chapter 8. Impacts of environmental toxicants and natural variables on the immune system of fishes 246
Chapter 9. Fish models of carcinogenesis 270
Chapter 10. Metallothionein: Structure and regulation 304
Chapter 11. Cell death: Investigation and application in fish toxicology 318
Part 4: Endocrine Aspects 344
Section a: Stress and HPI axis 344
Chapter 12. Adrenal toxicology: Environmental pollutants and the HPI axis 346
Chapter 13. Xenobiotic impact on corticosteroid signaling 380
Section b: Thyroid and Retinoids 410
Chapter 14. Thyroid hormones 412
Chapter 15. The biology and toxicology of retinoids in fish 428
Section c: Reproduction 444
Chapter 16. Vitellogenesis and endocrine disruption 446
Part 5: Emerging Areas 488
Chapter 17. Pharmaceuticals in the environment: Drugged fish? 490
Chapter 18. P-glycoproteins and xenobiotic efflux transport in fish 510
Species Index 550
Subject Index 554

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