Dictionary of Toxicology (eBook)

Ernest Hodgson, Michael Roe (Autoren)

eBook Download: PDF | EPUB

2014 | 3. Auflage
390 Seiten
Elsevier Science (Verlag)
978-0-12-420241-2 (ISBN)

Infos

Dictionary of Toxicology, Third Edition presents a compendium of definitions of all current toxicological terminology. This authoritative reference illustrates and describes words, concepts, acronyms and symbols for both the toxicological theory and applied risk assessment, as well as providing guidance on the correct selection of problematic, similar and frequently-misused terms. Written by one of the world's foremost experts in toxicology, and with each entry peer reviewed, Dictionary of Toxicology, Third Edition is an essential reference for all scientific, medical and legal professionals who work with or encounter the toxicological effects of contaminants on biological systems. New to this edition: an update on every entry and the inclusion of all terminology and concepts relating to molecular toxicology, nanotoxicology and computational toxicology. - Presents peer-reviewed definitions on the most up-to-date toxicological terms and concepts. - New edition includes definitions within the fields of molecular toxicology, nanotoxicology, computational toxicology and risk assessment.

Dr Ernest Hodgson, Distinguished Professor Emeritus, North Carolina State University and Executive Director, Foundation for Toxicology and Agromedicine was educated at King's College of the University of Durham (now the University of Newcastle), Oregon State University and the University of Wisconsin. At North Carolina State University since 1961 he was a William Neal Reynolds Professor and Head of the newly formed Department of Toxicology. He was also one of the founders of the three university (East Carolina University, North Carolina State University and North Carolina A&T University) program in agromedicine, an organization which led to the formation of the North Carolina Agromedicine Institute. Dr. Hodgson has conducted research on xenobiotic biochemistry for several decades, has authored c. 400 peer-reviewed papers in this area, and is editor and part author of several monographs. Most recently his research has focused on human studies utilizing human hepatocytes and sub-cellular preparations. Currently involved as a collaborator with Dr Michael Roe in RNAseq studies of genome-wide effects of environmental chemicals. From 1961 until his retirement he was supported by extramural funding, primarily from NIH (NIEHS) and the US Army. Dr Hodgson is also editor and contributing author of toxicology textbooks (Textbook of Modern Toxicology and Molecular and Biochemical Toxicology, both currently in their 4th editions) and is a lexicographer (Dictionary of Toxicology, under revision for a 3rd edition and a Dictionary of Agromedicine, being created for the NC Agromedicine Institute). He is well recognized for his role as a teacher of toxicology. In addition to his role as editor and part author of textbooks he has trained some 40 graduate students and 20 post-doctoral research associates. His service on federal study sections and other federal panels has been extensive and includes the following agencies. NIH, NASA, US Army and others. He has been recognized by awards from the Society of Toxicology, the American Chemical Society, the International Society for the Study of Xenobiotics, the Consolidated University of North Carolina and North Carolina State University. He is a past president of the International Society for the Study of Xenobiotics.

Inhalt

Front Cover 1
Dictionary of Toxicology 4
Copyright Page 5
Contents 6
About the Editors 8
Contributors to the Third Edition 12
Contributors to the First and Second Editions 14
Preface 18
Introduction 20
Dictionary of Toxicology 22
A 22
B 68
C 86
D 126
E 152
F 174
G 184
H 194
I 206
J 218
K 220
L 222
M 230
N 258
O 274
P 284
Q 316
R 318
S 328
T 350
U 376
V 380
W 384
X 386
Y 388
Z 390

Textauszug

About the Editors

Ernest Hodgson, distinguished professor emeritus, North Carolina State University and executive director, Foundation for Toxicology and Agromedicine was educated at King’s College of the University of Durham (now the University of Newcastle), Oregon State University, and the University of Wisconsin. At North Carolina State University, since 1961, he was a William Neal Reynolds Professor and head of the newly formed department of toxicology. He was also one of the founders of the three university (East Carolina University, North Carolina State University, and North Carolina A&T University) program in agromedicine, an organization which led to the formation of the North Carolina Agromedicine Institute.

He has conducted research on xenobiotic biochemistry for several decades, has authored c. 400 peer-reviewed papers in this area, and is editor and part author of several monographs. Most recently, his research has focused on human studies utilizing human hepatocytes and subcellular preparations. He is currently involved as a collaborator with Michael Roe in RNAseq studies of genome-wide effects of environmental chemicals. From 1961 until his retirement he was supported by extramural funding, primarily from NIH (NIEHS) and the US Army.

He is also an editor and contributing author of toxicology textbooks (Textbook of Modern Toxicology and Molecular and Biochemical Toxicology, both currently in their fourth editions) and is a lexicographer (Dictionary of Toxicology and a Dictionary of Agromedicine, being created for the NC Agromedicine Institute). He is well recognized for his role as a teacher of toxicology. In addition to his role as editor and part author of textbooks he has trained some 40 graduate students and 20 postdoctoral research associates.

His service on federal study sections and other federal panels has been extensive and includes the following agencies: NIH, NASA, US Army, and others. He has been recognized by awards from the Society of Toxicology, the American Chemical Society, the International Society for the Study of Xenobiotics, the Consolidated University of North Carolina, and North Carolina State University. He is a past president of the International Society for the Study of Xenobiotics.

R. Michael Roe, PhD, is a William Neal Reynolds Distinguished Professor in the department of entomology and the department of environmental and molecular toxicology at North Carolina State University (NCSU) in Raleigh, NC, and was elected as fellow in 2012. He is internationally recognized for his research in insect and acarine physiology, biochemistry, genomics, and toxicology, and the use of fundamental research in chemistry, nuclear science and biology to solve practical problems and develop new commercial technologies.

He was born in Plaquemine, LA, in 1952 where he graduated high school in 1970. He obtained his BS degree with a minor in chemistry from Louisiana State University (LSU) in Baton Rouge in 1974. He continued his graduate education at LSU obtaining a MS degree in physiology with a minor in biochemistry in 1976 and a PhD in entomology and a minor in nuclear science in 1981. He was an NIH fellow in Cellular and Molecular Biology in the department of entomology at the University of California at Davis from 1981–1984 and in 1984 accepted a position as assistant professor in entomology at North Carolina State University, Raleigh.

His laboratory focuses on understanding how insect and acarine systems function at the molecular level, the use of synthetic organic chemistry to understand structure-activity, and applications in bioassay, chemistry, molecular biology, and physics to solve practical pest problems in the context of integrated pest management. He is also interested on the impact of environmental chemicals on human health, focusing on global gene expression and epigenetics using primary human cells, risk assessment, and mechanisms of action. His lab is especially active in technology transfer and product development. Some of his greatest successes include a USEPA registered insect and tick repellent more effective than DEET and a fast acting, natural broad spectrum herbicide, among many others. He has been at NCSU for more than 30 years and is a prolific author with more than 250 published papers, 8 books, 36 patents, and 10 licensed technologies. He has been an invited speaker for more than 40 scientific events throughout the world and was the organizer of several national and international scientific meetings. He is the president of the company, InTox Biotech, in Middlesex, NC, and has served or is serving on the advisory boards for several companies and nonprofit organizations in the United States. He is also a founding member of the interdepartmental Biotechnology Program at NCSU which provides hands-on courses in molecular techniques and a minor in biotechnology and has developed new courses at NCSU in physiology, insect morphology, molecular entomology, toxicology, and professional development.

He has received several awards for his accomplishments. However, he considers his greatest professional successes and greatest joy in the more than 50 graduate students that he has trained as the committee advisor with MS and PhDs in chemistry, biochemistry, nuclear engineering, physiology, toxicology, biology, textile science, and entomology at NCSU. He has also trained over 20 postdoctoral researchers. His graduates and postdocs have gone on to successful careers in academia, industry, and government in the United States and throughout most of the world. He is married to Janet (Richard) Roe and has a son, Jonathan, and a daughter, Jennifer. His hobbies include work on his farm east of Raleigh, repairs on his MG, camping, and surf fishing on islands off the coast of NC.

Janice Chambers is a William L. Giles Distinguished Professor and Director of the Center for Environmental Health Sciences in the College of Veterinary Medicine at Mississippi State University. She is originally from Berkeley, CA, and she received her BS in biology from the University of San Francisco and her PhD in animal physiology from Mississippi State University. She has experience in pesticide toxicology with major emphases on: the effects of pesticides on the nervous and endocrine systems; the metabolism of pesticides; developments of neuroprotectants for organophosphate anticholinesterases; mechanisms by which pesticides cause toxicity; the levels of exposure of people to pesticides; and predicting the effects of mixtures of pesticides. Her current research activities involve: health disparities/minority health and the association of legacy pesticides with the prevalence of type 2 diabetes; characterization of biomarkers of risk of chronic disease; and the development of novel antidotes to nerve agents. She has received board certification in toxicology through both the American Board of Toxicology and the Academy of Toxicological Sciences. She has received the Education Award from the Society of Toxicology and the American Chemical Society International Award for Research in Agrochemicals. She has served on the executive boards and committees of several scientific organizations and the two toxicology certification organizations. She has also served on several advisory and review panels, including study sections for the National Institutes of Health and the Scientific Advisory Panel for the Federal Insecticide, Fungicide and Rodenticide Act for the US Environmental Protection Agency and the Human Studies Review Board for the USEPA. She has been the principal investigator of over US$25 million in federally funded competitive grants primarily from the National Institutes of Health, the Department of Defense/Defense Threat Reduction Agency and the US Environmental Protection Agency, and she has published over 125 articles in scientific journals, edited books, and book chapters, and over 300 abstracts from conference proceedings. She is actively engaged in graduate education.

Richard Mailman is Professor and College of Medicine Distinguished Senior Scholar of Pharmacology and Neurology at the Penn State University College of Medicine. He earned his PhD. in physiology/toxicology from North Carolina State University working with Dr. Ernest Hodgson where his major contribution was the first demonstration of multiple forms of cytochrome P450 in chemically-untreated animals. After post-doctoral training, he joined the faculty at the University of North Carolina School of Medicine where he rose to the rank of Professor and Director of the Division of Basic Psychobiology. In 2008, he was recruited to his current position at the Penn State College of Medicine. His research has focused on the pharmacology and toxicology of brain dopamine systems, and on mechanisms of ligand-receptor interactions.

Dr. Mailman is the author of more than 250 research papers, two books, six patents, and numerous pending patent applications. He has been a consultant for large and small pharma, several foundations, and has served continuously for several decades on Federal review groups, most recently as a member of the DDNS study section of the National Institutes of Health and as Chair of the Neurobiology E study section of the Veterans Administration. He currently serves on several editorial boards and as a regular peer reviewer for more than two-dozen journals. He is a Fellow of the American College of Neuropsychopharmacology, and has received several awards including the Burroughs-Wellcome Fund Scholar in Toxicology, and the Hargraves Award in Mental Health Research. He also has received...

Produkt-Details

• Erscheint lt. Verlag: 8.10.2014
• Sprache: englisch
• Themenwelt: Schulbuch / Wörterbuch ► Lexikon / Chroniken
• Themenwelt: Medizin / Pharmazie ► Medizinische Fachgebiete ► Arbeits- / Sozial- / Umweltmedizin
• Themenwelt: Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie
• ISBN-10: 0-12-420241-1 / 0124202411
• ISBN-13: 978-0-12-420241-2 / 9780124202412