Experimental and Clinical Neurotoxicology
Seiten
2000
|
2nd Revised edition
Oxford University Press Inc (Verlag)
978-0-19-508477-1 (ISBN)
Oxford University Press Inc (Verlag)
978-0-19-508477-1 (ISBN)
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This is the Bible of neurotoxicology. It is an essential reference work for any professional concerned with the neurotoxic potential of drugs, experimental agents, environmental pollutants, personal-use products, and other substances. The long-awaited Second Edition has been reorganized and completely rewritten to give encyclopedic coverage of almost 450 chemical compounds.
The first edition of this highly acclaimed reference work was published in 1980. Since then no other book has approached the breadth, scholarship and the balance of this book. For this long-awaited second edition, the original editors have been joined by Albert Ludolph, who brings in expertise in biological neurotoxicology.
In the introductory chapters, an overview of the biological basis of neurotoxicity provides the groundwork for discussing the scope of human and veterinary neurotoxic disease. The bulk of the text is devoted to an encyclopaedic treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic mechanisms of experimental agents and adverse effects of therapeutic and abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives and agents harboured by plants, animals and humans for use against their respective enemies are all included. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarised and cross-referenced in a series of appendices and an extensive index.
This book will be indispensable to experimental neuroscientists, toxicologists, and practitioners of human and animal medicine. It also provides an authoritative, critical and pithy reference work for public health specialists and those within the legal profession.
The first edition of this highly acclaimed reference work was published in 1980. Since then no other book has approached the breadth, scholarship and the balance of this book. For this long-awaited second edition, the original editors have been joined by Albert Ludolph, who brings in expertise in biological neurotoxicology.
In the introductory chapters, an overview of the biological basis of neurotoxicity provides the groundwork for discussing the scope of human and veterinary neurotoxic disease. The bulk of the text is devoted to an encyclopaedic treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic mechanisms of experimental agents and adverse effects of therapeutic and abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives and agents harboured by plants, animals and humans for use against their respective enemies are all included. Each substance is rated on a three-point scale for the weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarised and cross-referenced in a series of appendices and an extensive index.
This book will be indispensable to experimental neuroscientists, toxicologists, and practitioners of human and animal medicine. It also provides an authoritative, critical and pithy reference work for public health specialists and those within the legal profession.
Part I: Fundamentals of Experimental and Clinical Neurotoxicology
1: Peter S. Spencer: Biological Principles of Chemical Neurotoxicity
2: Herbert H. Schaumburg: Human Disease
3: Anthony A. Frank, Linda L. Blythe, and Peter S. Spencer: Aspects of Veterinary Neurotoxicity
Part II: Chemicals with Neurotoxic Potential
This section presents an encyclopedic description of 450 exogenous neurotoxic chemicals/ mixtures, beginning with Absinthe and ending with Zolpidem.
| Mitarbeit |
Stellvertretende Herausgeber: Albert C. Ludolph |
|---|---|
| Zusatzinfo | line figures |
| Verlagsort | New York |
| Sprache | englisch |
| Maße | 284 x 221 mm |
| Gewicht | 3331 g |
| Themenwelt | Schulbuch / Wörterbuch ► Lexikon / Chroniken |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie | |
| Studium ► 2. Studienabschnitt (Klinik) ► Pharmakologie / Toxikologie | |
| ISBN-10 | 0-19-508477-2 / 0195084772 |
| ISBN-13 | 978-0-19-508477-1 / 9780195084771 |
| Zustand | Neuware |
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