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New Generation Vaccines -

New Generation Vaccines

Buch | Hardcover
1040 Seiten
2009 | 4th edition
Crc Press Inc (Verlag)
978-1-4200-6073-7 (ISBN)
CHF 779,95 inkl. MwSt
Highlighting the latest activities and initiatives of prominent organizations working in the vaccine industry such as the Bill and Melinda Gates Foundation, The Global Alliance for Vaccines and Immunization, WHO, UNICEF, the World Bank, New Generation Vaccines, Fourth Edition, details steps developing countries have taken toward research, development, manufacture, and regulation of several new vaccines for widespread use.

This text will:



cover the current state-of-the-art techniques in vaccine development – including the successes and the failures
trace vaccine development from the bench to public health with regard to both FDA and European Union regulations
investigate improved methods for immunizing large populations, and the use of needless vaccinations
discuss the advancements in the heavily government-funded areas for developing vaccines against potential bioterror and infectious disease agents as well as the immunization of large population bases for diseases like: Anthrax, Smallpox, Ebola, West Nile, SARS, and others

Updated throughout with new cutting-edge information on recent breakthroughs and developments.

NEW TO GENERATION VACCINES, FOURTH EDITION:



highlights the latest activities of prominent organizations in the vaccine industry
covers the current techniques in vaccine development
investigates improved methods for immunizing large populations

Myrone M. Levine, Gordon Dougan, Michael F. Good, Gary J. Nabel, James P. Nataro, Rino Rappuoli

Vaccines and Vaccination in Historical Perspective. An Overview of Biotechnology in Vaccine Initial Clinical Evaluation of New Vaccine Candidates: Investigators' Perspective of Phase I and II Clinical Trials of Safety, Immunogenicity & Preliminary Efficacy Development. Clinical vaccine trials in developing countries Long-Term Evaluation of Vaccine Protection: Methodological Issues for Phase III and IV Studies (including designs to measure herd immunity). Ethical Considerations in the Conduct of Vaccine Trials in Developing Countries Vaccine Economics: From Candidates to Commercialized Products in the Developing World (will include new G8 financing mechanisms). Development and Supply of Vaccines: An Industry Perspective Reaching Every Child - Achieving Equity in Global Immunization A Paradigm for International Cooperation: the Global Alliance for Vaccines and Immunization (GAVI) and the Vaccine Fund Economic Analyses of Vaccines and Vaccination Programs The Role of the Food and Drug Administration and other Industrialized Country Regulatory Agencies in Vaccine Testing and Licensure Strengthening Regulatory Agencies in Developing Countries Developing Safe Vaccines A Primer on Large-Scale Manufacture of Modern Vaccines. Polio Eradication: Ever Closer to a Worthy but Elusive Goal Full Genome Sequence Analysis (Data Mining) and Bioinformatics Overview of Reverse Vaccinology Recent Advances in Immunology that Impact Vaccine Development How the Innate Immune System Affects Adaptive Immune Responses to Vaccines Immunodominance, Deceptive Imprinting & B Cell Mimotopes Standardization and High-Throughput Measurement of T-Cell and B-Cell Responses to Vaccines The Challenge of Inducing Protection in Very Young Infants and the Elderly. Vaccination and Autoimmunity An Overview of Adjuvants for the Future Immune-Enhancing Sequences (CpG Motifs), Cytokines, and Other Immunomodulatory Moieties. Use of Genetically Detoxified Mutants of Cholera and Escherichia coli Hea

Erscheint lt. Verlag 9.12.2009
Zusatzinfo 100 Illustrations, black and white
Verlagsort Bosa Roca
Sprache englisch
Maße 210 x 280 mm
Gewicht 2540 g
Themenwelt Sachbuch/Ratgeber Gesundheit / Leben / Psychologie
Medizin / Pharmazie Allgemeines / Lexika
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie
Technik
ISBN-10 1-4200-6073-2 / 1420060732
ISBN-13 978-1-4200-6073-7 / 9781420060737
Zustand Neuware
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