Organ Directed Toxicities of Anticancer Drugs
Springer-Verlag New York Inc.
978-1-4612-9205-0 (ISBN)
Keynote Address.- The Irrelevant Toxicities of Anticancer Drugs.- Section I: Anthracycline Induced Cardiotoxicity.- Overview.- Role of Iron in Anthracycline Action.- Role of Reactive Oxygen Production in Doxorubicin Cardiac Toxicity.- Adriamycin Cardiac Toxicity — An Assessment of Approaches to Cardiac Monitoring and Cardioprotection.- Pretreatment with ICRF-187 Protects Against the Chronic Cardiac Toxicity Produced by Very Large Cumulative Doses of Doxorubicin in Beagle Dogs.- A Trial of ICRF-187 to Selectively Protect Against Chronic Adriamycin Cardiac Toxicity: Rationale and Preliminary Results of a Clinical Trial.- Section II: Bleomycin Induced Pulmonary Toxicity.- Overview.- Base Propenals and the Toxicity of Bleomycin.- Bleomycin Induced Lung Injury.- Immunoregulation of Growth Factor Release in Bleomycin Induced Lung Disease.- Pulmonary Toxicity of Anticancer Drugs: Alterations in Endothelial Cell Function.- Pulmonary Metabolic Inactivation of Bleomycin and Protection from Drug Induced Lung Injury.- Biochemical and Molecular Bases of Bleomycin Induced Pulmonary Fibrosis: Glucocorticoid Intervention.- Section III: Platinum Induced Nephrotoxicity.- Overview.- Factors Influencing the Formation and Persistence of Platinum-DNA Adducts in Tissues of Rats Treated with Cisplatin.- Cisplatin Nephrotoxicity: New Insights into Mechanism.- Experimental Approaches to Reducing Platinum Induced Kidney Toxicity.- High Dose Cisplatin with Hypertonic Saline: Toxicity and Therapeutic Results.- Section IV: Poster Presentations.- Titles and Authors.- Abstracts.- Author Index.
Reihe/Serie | Developments in Oncology ; 53 |
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Zusatzinfo | XII, 254 p. |
Verlagsort | New York, NY |
Sprache | englisch |
Maße | 155 x 235 mm |
Themenwelt | Sachbuch/Ratgeber ► Natur / Technik ► Garten |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie | |
Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie | |
ISBN-10 | 1-4612-9205-0 / 1461292050 |
ISBN-13 | 978-1-4612-9205-0 / 9781461292050 |
Zustand | Neuware |
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