Metabolic Maps (eBook)

Pesticides, Environmentally Relevant Molecules and Biologically Active Molecules

Hiroyasu Aizawa (Autor)

eBook Download: PDF

2001 | 1. Auflage
330 Seiten
Elsevier Science (Verlag)
978-0-08-053629-3 (ISBN)

Infos

People working in development of drugs, pesticides, washing detergents, etc., are obliged by law to conduct analyses of the metabolic pathways or maps for the chemical compounds that they are using or proposing.
Everyone in these industries or carrying out research toward such products is therefore interested in having a reference on these compounds.

Key Features
* Covers literature relating to degradation and metabolic profiles of molecules
* Draws together the literature on degradation and metabolism patterns with that on diversified conditions of the environmental systems
* Indicates 3D chemical structures, predicted physico-chemical parameters, logP and the SMILES chemical notations of the parent compounds to assist scientists design the lead compounds for new discovery using computer-aided technology

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People working in development of drugs, pesticides, washing detergents, etc., are obliged by law to conduct analyses of the "e;metabolic pathways"e; or "e;maps"e; for the chemical compounds that they are using or proposing. Everyone in these industries or carrying out research toward such products is therefore interested in having a reference on these compounds. Covers literature relating to degradation and metabolic profiles of molecules Draws together the literature on degradation and metabolism patterns with that on diversified conditions of the environmental systems Indicates 3D chemical structures, predicted physico-chemical parameters, logP and the SMILES chemical notations of the parent compounds to assist scientists design the lead compounds for new discovery using computer-aided technology

Inhalt

Front Cover 1
Metabolic Maps 4
Copyriht Page 5
Contents 6
Preface 14
Chapter 1. Acid Amides 16
Acetaminophen (APAP) 17
Acetochlor 18
Alachlor 19
Benalaxyl 22
Butachlor 23
Carpropamid 24
Chloramphenicol 25
Cisapride 26
2,6-Dichlorobenzamide (DCB) 27
N,N-Diethyl-meta-toluamide (DEET) 28
N-(2,6-Dimethylphenyl)-4-[[(diethylamino)acetyl]amino]benzamide (DEGA) 30
N,N-Diethylphenylacetamide (DEPA) 31
N,N-Dimethylformamide (DMF) 32
N-Ethyl-N-methyl-4-(trifluoromethyl)-2-(3,4-dimethoxyphenyl)benzamide (EMTDB) 33
Epicainide 34
Furalaxyl 35
Inabenfide 36
Isobutylphendienamide [(2E,4E)-N-lsobutyl-6-phenylhexa-2,4-dienamide] 38
Metalaxyl (Ridomil) 40
Metazachlor 41
N-(Methylisothiazolin-5-ylidene)phenylacetamide (ITOPA) 42
Metolachlor 43
Naproanilide 44
Oxycarboxin 46
Prinomide (CGS 10787B) 47
Thenylchlor (NSK-850) 48
Trifoline (Saprol) 49
Chapter 2. Amidines, Guanidines, and Hydrazines 50
Amdro (AC 217,300) 51
Amitraz (Mitac/Tactic) 52
Daminozide (Alar) 53
Guazatine triacetate (Befran) 54
Chapter 3. Amino Acid–Phosphinic Acids 55
Bialaphos 56
Phosphinothricin 57
Chapter 4. Anilines and Nitrobenzenes 58
4-Aminobiphenyl and 4,4'-Methylene-bis-(2-chloroaniline) 59
1,3-Diaminobenzene (m-Phenylenediamine) 60
3,4-Dichloroaniline 61
2,6-Dichloro-4-nitroaniline (DCNA) 62
2,6-Dieth ylaniline (DEA) 63
2,4- and 2,6-Dimethylanilines 64
2,4-Dinitrophenol 66
2,4-Dinitrotoluene (2,4-DNT) 67
2,6-Dinitrotoluene (2,6-DNT) 68
2-, 3- and 4-Fluoroanilines 69
Diphenylamine 70
4-Nitrophenol 71
Pendimethalin 72
Chapter 5. Aryloxy Acids 74
2,4-D and 2,4-DP 75
Diclofop methyl 77
Fenoxaprop ethyl 78
Fluazifop butyl 79
Haloxyfop methyl 80
Trichlopyr 81
Chapter 6. Biphenyl Ethers 82
Chlornitrofen (MC-338) 83
Fluorodifen 84
Preforan, Nitrofen, MC-338, MC-4379, MC-3761, MC-5127, MC-6063, and MC-7181 85
Chapter 7. Carbamates 89
Aminocarb (Matacil) 90
Benfuracarb 91
Carbetamide 92
Diethofencarb 94
Fenoxycarb 95
Pirimicarb 96
Chapter 8. Dithio- and Thiolcarbamates 97
Cartap hydrochloride 98
EPTC 99
Fenothiocarb 100
Fenothiocarb sulfoxide 102
Molinate (Ordram) 103
Orbencarb 105
Chapter 9. Halogenated Aliphatics 106
1,2-Dibromoethane 107
1,2-Dichloroethane 107
1,3-Dichloropropene 109
Dichloroacetylene 110
Endosulfan 111
Hexachloro-1,3-butadiene 112
Trichloroethylene 113
Chapter 10. Halogenated Aromatics 114
Bromobenzene and Chlorobenzene 115
Chlorothalonil (Daconil) 116
DDT 118
1,4-Dichlorobenzene 120
2,6-Dichlorobenzonitrile (DCBN) and 2,6-Dichlorothiobenzamide (DCTBA) 121
Hexachlorobenzene 123
Methoxychlor 124
2,2',4,4',5-Pentachlorodiphenyl ether (PCDE) 125
3,4,3'4'-Tetrachlorobiphenyl 126
2,3,7,8-, 1,3,6,8- and 1,2,3,4-Tetrachlorodibenzo-p-dioxins (TCDDS) 129
Chapter 11. Five-membered Heterocycles 130
2-N-Dodecyltetrahydrothiophene (DTHT) and 2-N-Undecyltetrahydrothiophene (UTHT) 131
Assert (isomeric mixture of methyl 6-(isopropyl-4-methyl-5oxo-2-imidazolin-2-yl) Meta-toluate and methyl 2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)-para-to luate) 133
Azocyclotin 134
Carfentrazone 135
Clomazone (FMC57020) 136
Croconazole 138
F5231 139
Fenpyroximate 140
Fipronil 142
Flurochloridone 143
5-Hydroxymethyl-2-f uraldehyde 145
Hymexazol O- and N-glucosides 146
Imidacloprid 148
Isoprothiolane/lsoprothiolane sulfoxide 150
Methaphenilene and Pyribenzamine 151
Methapyrilene 153
5-Methyl-2-furaldehyde 154
1-Methylhydantoin 155
N-Methyl-2-pyrrolidinone (NMP) 156
N-Nitroso-1,3-thiazolidine 157
Oxaminozoline 158
Propiconazole 160
Pyrazolate 161
Spiroxamine (KWG4168) 162
Sulfentrazone (F6285) 165
Tebufenpyrad 166
a-Terthienyl 168
Triadimenol 169
2,4,5-Trihaloimidazoles 170
Vinclozolin 172
Chapter 12. Five-membered Heterocycles (fused) 173
Azafenidin 174
Benlate (Benomyl) andzim Carbendazim 175
Carbendazim 176
Cinmethylin 177
Cloransulam methyl 178
Fluthiacet methyl (KIH-9281) 179
Indole 180
Methabenzthiazuron 181
3,4-(Methylenedioxy)methamphetamine 182
2-Methylthiobenzothiazole 184
Omeprazole 185
Pindolo 186
Skatole 187
Chapter 13. Six-/more membered Heterocycles 188
Bispyribac sodium 189
Bromacil 190
Buprofezn (Applaud) 191
Cycloxydim 192
Cyprodinil 193
2-Dimethylamino-5,6-dimethylpyrimidin-4-ol 194
7-N,N-Dimethylamino-1,2,3,4,5-pentathiocyclooctane (PTCA) 195
Indeloxazine hydrochloride 196
Mepanipyrim 197
N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine 198
Phencyclidine 199
Terbacil 200
Chapter 14. Six-/more membered Heterocycles (fused) 201
Benoxacor 202
Bentazon 204
Chlorpromazine 205
Chlorpromazine N-oxide 206
Fluperlapine 207
Idazoxan 208
Quinoline-4-carboxylic acid 209
SC-1271 210
SK& F 86466
Chapter 15. Imides 212
Aminoglutethimide 213
N-(Bromophenyl)-3,4,5,6-tetrahydroisophthalimide and 5-(4-Bromophenylimino)-,3,4-tetramethylene-1,3,4-thiadiazolidin-2-one 214
Chlozolinate, Vinclozolin, and Procymidone 216
N-(3,5-Dichlorophenyl) succinimide (NDPS) 218
Flumiclorac pentyl (S-23031) 219
Flumipropyn (S-23121) 220
MK-129 221
Procymidone (Sumilex, S-7131) 222
S-53482 224
Chapter 16. Natural Products 225
(+)- and (-)-Abscisic acids 226
Aflatoxin B1 227
Aspartame 228
Azadirachtin 229
Blasticidin S 230
Brassicanal A 231
24-epi-Brassinolide 232
Ecdysone 234
7-Ethoxycoumarin and Androstenedione 235
Kadsurenone and 9,10-Dihydrokadsurenone 236
Rotenone 238
Spinosad 239
Zearalenone 241
Chapter 17. Organophosphorous Compounds 242
Azinphos methyl 243
Butamifos (Cremart) and its isomer 244
Coumaphos 245
Phosalone 246
Quinalphos 247
Chapter 18. Oximes 248
Aldicarb 249
BAS 490 F (Kresoxim methyl) 250
Chapter 19. Phenylureas and Related Compounds 251
Isoproturon 252
Linuron and Chlorbromuron 253
Metoxuron 255
Pencycuron 256
Chapter 20. Phosphono Amino Acids and Related Compounds 257
Glyphosate (Roundup) 258
Isofenphos 259
Chapter 21. Pyrethroids 260
Bifenthrin 261
Cyfluthrin 262
Cyhalothrin 263
Cypermethrin 265
Deltamethrin 266
Fenvalerate 268
Fluvalinate 269
cis- and trans-Resmethrins 270
Tefluthrin 271
Chapter 22. Sulfonylureas 272
Amidosulfuron 273
Bensulfuron methyl 274
Chlorimuron ethyl 276
Chlorsulfuron 278
Metsulfuron methyl 280
Nicosulfuron 282
Prosulfuron 283
Rimsulfuron 285
Sulfometuron methyl 287
Thifensulfuron methyl 288
Triasulfuron 290
Tribenuron methyl 292
Chapter 23. Triazines and Related Compounds 294
Hexazinone 295
Irgarol 1051 296
Metamitron 297
Chapter 24. Miscellaneous 298
Acrolein (Magnacide H) 299
Butyl acrylate 300
2,3-Dimercaptopropane-1-sulfonic acid (DMPS) 301
2-Nitrofluorene (NF) 302
References 303
Predicted parameters of log P 311
Author Index 323
Activity Index 332
Subject Index 336

Produkt-Details

• Erscheint lt. Verlag: 31.5.2001
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Ökologie / Naturschutz
• Themenwelt: Naturwissenschaften ► Biologie ► Zoologie
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 0-08-053629-8 / 0080536298
• ISBN-13: 978-0-08-053629-3 / 9780080536293