International Review of Cell and Molecular Biology (eBook)

Kwang W. Jeon (Herausgeber)

eBook Download: PDF

2009 | 1. Auflage
368 Seiten
Elsevier Science (Verlag)
978-0-08-088496-7 (ISBN)

Infos

International Review of Cell & Molecular Biology presents current advances and comprehensive reviews in cell biology-both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth.

* Authored by some of the foremost scientists in the field
* Provides up-to-date information and directions for future research
* Valuable reference material for advanced undergraduates, graduate students and professional scientists

Inhalt

Front Cover 1
International Review of Cell and Molecular Biology 4
Copyright Page 5
Contents 6
Contributors 10
Chapter 1: Genetic Models of Cancer in Zebrafish 12
1. Introduction 13
2. Molecular Relevance of Zebrafish Cancer to Human Disease 16
3. Forward Genetic Screens 17
4. Targeted Cancer Models in Zebrafish 21
5. Xenotransplantation 34
6. Chemical Genetics: Small-Molecule Screening in Zebrafish 37
7. Summary 38
Acknowledgments 38
References 39
Chapter 2: Cellular and Molecular Biological Aspects of Cervical Intraepithelial Neoplasia 46
1. Introduction 47
2. Cervical Cancer as a Unique Model of Human Carcinogenesis 48
3. Biology of Cervical Neoplasias 51
4. Cellular Aspects of Cervical Tumors Progression 55
5. Molecular Aspects of Cervical Carcinogenesis 62
6. Conclusions 86
References 87
Chapter 3: Vesicle, Mitochondrial, and Plastid Division Machineries with Emphasis on Dynamin and Electron-Dense Rings 108
1. Introduction 109
2. Structural Similarities Among Mitochondrial, Plastid, and Vesicle Division Machineries 112
3. Vesicle Division Machinery 118
4. Bacterial, Microbody (Peroxisome), Mitosome, and Hydrogenosome Division Machineries 122
5. Mitochondrial Division Machinery 129
6. Plastid (Chloroplast) Division Machinery 139
7. Isolation of Organelle Division Machinery and its Significance 148
8. Concluding Remarks 154
Acknowledgments 155
References 155
Chapter 4: Retromer: Multipurpose Sorting and Specialization in Polarized Transport 164
1. Introduction: Basic Concepts on Coat-Mediated Vesicular Transport 165
2. Retromer's Assembly and Functioning 166
3. Multiple Roles of Retromer: Models of Study 171
4. Polarized Transport Mediated by Retromer 178
5. Implication of Retromer and Sorting Nexins in Other Aspects of Polarity 190
6. Concluding Remarks 195
Acknowledgments 196
References 196
Chapter 5: Translational Control of Gene Expression: From Transcripts to Transcriptomes 210
1. Introduction 211
2. Preparation for Translation: RNA Processing and Export 213
3. Regulation of Translation 215
4. Emerging Concepts in Translational Regulation 230
5. Global Approaches to Identify Targets of Posttranscriptional Gene Regulation 238
6. Concluding Remarks 248
Acknowledgments 249
References 249
Chapter 6: Phagocytosis and Host-Pathogen Interactions in Dictyostelium with a Look at Macrophages 264
1. Introduction 265
2. The Dynamics of Phagocytosis 268
3. Cellular Mechanisms of Phagocytosis 271
4. Regulatory Pathways Controlling Phagocytosis 279
5. Host-Pathogen Interactions: A Versatile New Model Host 292
6. Concluding Remarks 299
Acknowledgments 300
References 300
Chapter 7: Mechanobiology of Adult and Stem Cells 312
List of Abbreviations 313
1. Introduction 314
2. Application of External Mechanical Forces to Cells 315
3. Cell-Generated Mechanical Forces 317
4. Mechanobiological Responses of Cells 322
5. Mechanotransduction Mechanisms 340
6. Concluding Remarks 343
Acknowledgment 345
References 345
Index 358

Produkt-Details

• Erscheint lt. Verlag: 24.2.2009
• Sprache: englisch
• Themenwelt: Sachbuch/Ratgeber
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Biologie ► Zellbiologie
• Themenwelt: Technik
• ISBN-10: 0-08-088496-2 / 0080884962
• ISBN-13: 978-0-08-088496-7 / 9780080884967