Error-Tolerant Biochemical Sample Preparation with Microfluidic Lab-on-Chip (eBook)

Bhargab B. Bhattacharya, Sudip Poddar (Autoren)

eBook Download: PDF

2022
222 Seiten
CRC Press (Verlag)
978-1-000-61270-7 (ISBN)

Infos

Microfluidic biochips have gained prominence due to their versatile applications to biochemistry and health-care domains such as point-of-care clinical diagnosis of tropical and cardiovascular diseases, cancer, diabetes, toxicity analysis, and for the mitigation of the global HIV crisis, among others. Microfluidic Lab-on-Chips (LoCs) offer a convenient platform for emulating various fluidic operations in an automated fashion. However, because of the inherent uncertainty of fluidic operations, the outcome of biochemical experiments performed on-chip can be erroneous even if the chip is tested a priori and deemed to be defect-free. This book focuses on the issues encountered in reliable sample preparation with digital microfluidic biochips (DMFBs), particularly in an error-prone environment. It presents state-of-the-art error management techniques and underlying algorithmic challenges along with their comparative discussions. Describes a comprehensive framework for designing a robust and error-tolerant biomedical system which will help in migrating from cumbersome medical laboratory tasks to small-sized LOC-based systems Presents a comparative study on current error-tolerant strategies for robust sample preparation using DMFBs and reports on efficient algorithms for error-tolerant sample dilution using these devices Illustrates how algorithmic engineering, cyber-physical tools, and software techniques are helpful in implementing fault tolerance Covers the challenges associated with design automation for biochemical sample preparation Teaches how to implement biochemical protocols using software-controlled microfluidic biochips Interdisciplinary in its coverage, this reference is written for practitioners and researchers in biochemical, biomedical, electrical, computer, and mechanical engineering, especially those involved in LOC or bio-MEMS design.

Produkt-Details

• Erscheint lt. Verlag: 27.7.2022
• Sprache: englisch
• Themenwelt: Medizin / Pharmazie ► Pflege
• Themenwelt: Medizin / Pharmazie ► Physiotherapie / Ergotherapie ► Orthopädie
• Themenwelt: Medizin / Pharmazie ► Studium ► 1. Studienabschnitt (Vorklinik)
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Chemie ► Technische Chemie
• Themenwelt: Recht / Steuern ► EU / Internationales Recht
• Themenwelt: Recht / Steuern ► Privatrecht / Bürgerliches Recht ► Medizinrecht
• Themenwelt: Technik ► Elektrotechnik / Energietechnik
• Themenwelt: Technik ► Maschinenbau
• Themenwelt: Technik ► Medizintechnik
• Themenwelt: Technik ► Umwelttechnik / Biotechnologie
• ISBN-10: 1-000-61270-8 / 1000612708
• ISBN-13: 978-1-000-61270-7 / 9781000612707