Modern Biophysical Chemistry
Wiley-VCH (Verlag)
978-3-527-32360-9 (ISBN)
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The only introductory text to address contemporary methods, the really interesting stuff to spice up a standard biophysics courseis to be found here. Accessible and didactically written, it is based on a graduate course taught by the author for several years. By presenting a mix of basic theory and real life application examples, he successfully bridges the gap between theory and experiment.Divided into three major parts, this advanced textbook explains all relevant methods used in current industrial research. The first part, basic biophysical chemistry, surveys basic spectroscopic techniques and properties that are the prerequisite for the more sophisticated technologies discussed in the remainder of the book. The second part covers modern, cutting-edge bioanalytical techniques based on physical methods, such as confocal fluorescence, ultrafast spectroscopy, optical tweezers, single molecule electrical measurements, quantum dots, and single molecule force microscopy. The third part addresses the specific requirements of industry-scale methods, such as high-throughput and automatisation.Readers with a basic understanding of biochemistry and/or biophysics will quickly gain an overview of current technology for the biophysical analysis of proteins, nucleic acids and other biomolecules and their interactions. Equally, any student contemplating a career in the chemical, pharmaceutical or bio-industry will greatly benefit from the technological knowledge presented.
Peter J. Walla is a group leader at the Max-Planck-Institute for Biophysical Chemistry in Göttingen (Germany), and Professor for Biophysical Chemistry at the University of Braunschweig. Having obtained his academic degrees from the Universities of Heidelberg and Göttingen, Professor Walla did postdoctoral research at the University of California at Berkeley, and headed a department in a Biotech company co-founded by Nobel Laureate Manfred Eigen, before taking up his current position.
Introduction: What is Biophysical Chemistry?
PART 1: BASIC METHODS IN BIOPHYSICAL CHEMISTRY
Basic Optical Principles
Optical Properties of Biomolecules
Basic Fluorescence Techniques
Chiroptical and Scattering Methods
Magnetic resonance techniques
Mass spectrometry
PART 2: ADVANCED METHODS IN BIOPHYSICAL CHEMISTRY
Fluorescence Microscopy
Super-Resolution Fluorescence Microscopy
Ultrafast and Nonlinear Spectroscopy
DNA Sequencing and Next Generation Sequencing Methods
Assay Development, Readers and High-Throughput Screening
| Erscheint lt. Verlag | 26.2.2009 |
|---|---|
| Sprache | englisch |
| Maße | 170 x 240 mm |
| Gewicht | 610 g |
| Einbandart | Paperback |
| Themenwelt | Naturwissenschaften ► Chemie ► Organische Chemie |
| Schlagworte | Analytische Chemie • Biochemie • Biomolekül • Biophysikalische Chemie • Spektroskopie |
| ISBN-10 | 3-527-32360-0 / 3527323600 |
| ISBN-13 | 978-3-527-32360-9 / 9783527323609 |
| Zustand | Neuware |
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