Cell Junctions

Adhesion, Development, and Disease

Susan E. La Flamme, Andrew P. Kowalczyk (Herausgeber)

Buch | Hardcover

XVI, 302 Seiten

2008 | 1., Auflage
Wiley-VCH (Verlag)
978-3-527-31882-7 (ISBN)

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This long-awaited, first comprehensive book on this topic of fundamental importance in our understanding of cancer begins withan overview of cellular junctions, before covering cell-matrix junctions, cell-cell junctions and cell-matrix and cell-cell adhesion in separate sections.Of high interest to cell and molecular biologists, cancer researchers, oncologists, biochemists, pharmaceutists and those working in the pharmaceutical industry.

Susan LaFlamme is a professor in the Center for Cell Biology and Cancer Research at the Albany Medical College in Albany NY. She obtained her B.A. from Barnard College and her PhD from Columbia University in New York NY, USA. Professor LaFlamme has received many grants for her studies on integrin signaling and has published extensively in this area. She has served on review panels for the National Institutes of Health, the American Cancer Society and the American Heart Association. Andrew Kowalczyk is an Associate Professor for Cell Biology and Dermatology at Emory School of Medicine in Atlanta GA, USA. Dr. Kowalczyk obtained his PhD at Albany Medical School in Albany NY and carried out postdoctoral studies at Northwestern University Medical School in Chicago IL, USA. He has received numerous grants and awards and has published extensively in the area of cell adhesion. He has served on review panels for the National Institutes of Health and the American Heart Association, and on several advisory committees for the Society for Investigative Dermatology.

Overview of Cellular Junctions
CELL-MATRIX JUNCTIONS
Integrin Transmembrane Signaling
Focal Adhesion
Signaling Through FAK
Focal Adhesion Dynamics
Integrin Trafficking
Hemidesmosomes
Cell Matrix Adhesion in 3 Dimensions
CELL-CELL JUNCTIONS
Epithelial Adherens Junctions
Endothelial Adherens Junctions
Gap Junctions
Tight Junctions
Desmosomes
Junctions Dynamics and Adhesion Receptor Trafficking
CELL-MATRIX AND CELL-CELL CROSSTALK
Adhesion Receptors in Mechanotransduction
Crosstalk Between Cell-Cell and Cell-Matrix Adhesion

Erscheint lt. Verlag	3.4.2008
Sprache	englisch
Maße	170 x 240 mm
Gewicht	735 g
Einbandart	gebunden
Themenwelt	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
Schlagworte	Onkologie • Zellbiologie
ISBN-10	3-527-31882-8 / 3527318828
ISBN-13	978-3-527-31882-7 / 9783527318827
Zustand	Neuware