Drug Metabolism

Chemical and Enzymatic Aspects

Jack P. Uetrecht, William Trager (Autoren)

Buch | Hardcover

180 Seiten

2007
Crc Press Inc (Verlag)
978-0-8493-7595-8 (ISBN)

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In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structure and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market. This title is a comprehensive guide for recognizing the chemical underpinnings of drug metabolism. While there are numerous resources available to medicinal chemists for understanding drug structure, and to pharmacologists for discerning drug metabolism from a biological standpoint, no resource currently exists that links the chemical and biological aspects in language accessible to both-making it challenging for both groups to fully comprehend how a drug is metabolized, as well as the potential effects of the metabolites. Drug Metabolism: Chemical and Enzymatic Aspects provides extensive material to help understand drug metabolism within a biological context, and for predicting and mitigating adverse drug reactions.

Uetrecht, Jack P. | Trager, William

Background for Non-Chemists. Background for Chemists. Oxidation Pathways and the Enzymes That Mediate Them. Reductive Pathways. Hydolytic Pathways. Conjugation Pathways. Reactive Metabolites

Erscheint lt. Verlag	20.6.2007
Verlagsort	Bosa Roca
Sprache	englisch
Maße	178 x 254 mm
Gewicht	498 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Naturwissenschaften ► Biologie
	Naturwissenschaften ► Chemie
	Technik
ISBN-10	0-8493-7595-9 / 0849375959
ISBN-13	978-0-8493-7595-8 / 9780849375958
Zustand	Neuware