Protein Misfolding, Aggregation and Conformational Diseases
Springer-Verlag New York Inc.
978-0-387-36529-9 (ISBN)
Altered Protein Structure and Enhanced Aggregation/Deposition.- The Pathogenesis of Alzheimer’s Disease: General Overview.- Free Radicals, Metal Ions, and A? Aggregation and Neurotoxicity.- Progress in Understanding the Mechanisms of Neuronal Dysfunction and Degeneration in Parkinson’s Disease.- ?-Synuclein Aggregation and Parkinson’s Disease.- Cell Biology of ?-Synuclein: Implications in Parkinson’s Disease and Other Lewy Body Diseases.- Pathogenesis of Prion Diseases.- Mammalian Prion Protein.- The Yeast Prion Proteins Sup35p and Ure2p.- Immunoglobulin Light Chain and Systemic Light-Chain Amyloidosis.- Pancreatic Islet Amyloid and Diabetes.- ?2-Microglobulin and Dialysis-Related Amyloidosis.- Serum Amyloid A and AA Amyloidosis.- Point Mutations and Enhanced Protein Deposition.- Transthyretin and the Transthyretin Amyloidoses.- Human Lysozyme.- Serpins and the Diversity of Conformational Diseases.- Altered Protein Structure and Impaired Function.- Human Copper-Zinc Superoxide Dismutase and Familial Amyotrophic Lateral Sclerosis.- Understanding the Effects of Cancer-Associated Mutations in the Tumor Suppressor Protein p53: Structural Consequences of Mutations and Possible Ways of Rescuing Oncogenic Mutants.- Changes in Supramolecular Structure.- Protein Aggregation in Muscle Fibers and Respective Neuromuscular Disorders.- Muscular Dystrophies and Protein Mutations.- The Functional Consequences of Dystrophin Deficiency in Skeletal Muscles.- Eye Lens Proteins and Cataracts.- Altered Protein Structure and Changes in Cellular/Nuclear Function.- Glutamine/Asparagine-Rich Regions in Proteins and Polyglutamine Diseases.- Mechanistic Insights into the Polyglutamine Ataxias.- Molecular Pathogenesis of the Polyglutamine Disease: Spinal and Bulbar Muscular Atrophy.-Post-Translational Modification and Protein Conformational Diseases.- Protein Glycation and Cataract: A Conformational Disease.- Defective Glycosylation and Muscular Dystrophies.
| Reihe/Serie | Protein Reviews ; 6 |
|---|---|
| Zusatzinfo | 14 Illustrations, color; 98 Illustrations, black and white; XXVI, 538 p. 112 illus., 14 illus. in color. |
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Themenwelt | Studium ► Querschnittsbereiche ► Infektiologie / Immunologie |
| Naturwissenschaften ► Biologie ► Biochemie | |
| Naturwissenschaften ► Biologie ► Zellbiologie | |
| ISBN-10 | 0-387-36529-X / 038736529X |
| ISBN-13 | 978-0-387-36529-9 / 9780387365299 |
| Zustand | Neuware |
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