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Discovering Biomolecular Mechanisms with  Computational Biology -

Discovering Biomolecular Mechanisms with Computational Biology

Frank Eisenhaber (Herausgeber)

Buch | Hardcover
147 Seiten
2006
Springer-Verlag New York Inc.
978-0-387-34527-7 (ISBN)
CHF 224,65 inkl. MwSt
An anthology that presents critical reviews of methods and high-impact applications in computational biology that lead to results that non-bioinformaticians must also know to design efficient experimental research plans. It also explores the methodology of translating sequence strings into biological knowledge.
In this anthology, leading researchers present critical reviews of methods and high-impact applications in computational biology that lead to results that also non-bioinformaticians must know to design efficient experimental research plans. Discovering Biomolecular Mechanisms with Computational Biology also summarizes non-trivial theoretical predictions for regulatory and metabolic networks that have received experimental confirmation.


Discovering Biomolecular Mechanisms with Computational Biology is essential reading for life science researchers and higher-level students that work on biomolecular mechanisms and wish to understand the impact of computational biology for their success.

Prediction of Post-translational modifications from amino acid sequence: Problems, pitfalls, methodological hints.- Deriving Biological Function of Genome Information with Biomolecular Sequence and Structure Analysis.- Reliable and Specific Protein Function Prediction by Combining Homology with Genomic(s) Context.- Clues from Three-Dimensional Structure Analysis and Molecular Modelling.- Prediction of Protein Function.- Complementing Biomolecular Sequence Analysis with Text Mining in Scientific Articles.- Extracting Information for Meaningful Function Inference through Text-Mining.- Literature and Genome Data Mining for Prioritizing Disease-Associated Genes.- Mechanistic Predictions from the Analysis of Biomolecular Networks.- Model-Based Inference of Transcriptional Regulatory Mechanisms from DNA Microarray Data.- The Predictive Power of Molecular Network Modelling.- Mechanistic Predictions from the Analysis of Biomolecular Sequence Populations: Considering Evolution for Function Prediction.- Theory of Early Molecular Evolution.- Hitchhiking Mapping.- Understanding the Functional Importance of Human Single Nucleotide Polymorphisms.- Correlations between Quantitative Measures of Genome Evolution, Expression and Function.

Reihe/Serie Molecular Biology Intelligence Unit
Zusatzinfo 1 Illustrations, color; 41 Illustrations, black and white; XI, 147 p. 42 illus., 1 illus. in color.
Verlagsort New York, NY
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Mikrobiologie / Infektologie / Reisemedizin
Medizin / Pharmazie Studium
Naturwissenschaften Biologie Biochemie
ISBN-10 0-387-34527-2 / 0387345272
ISBN-13 978-0-387-34527-7 / 9780387345277
Zustand Neuware
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