Alzheimer's Disease
Advances in Genetics, Molecular and Cellular Biology
Seiten
2006
Springer-Verlag New York Inc.
978-0-387-35134-6 (ISBN)
Springer-Verlag New York Inc.
978-0-387-35134-6 (ISBN)
Examines major aspects of Alzheimer disease. This title includes coverage of the cellular-level exploration of related dementing disorders, presenting prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
This book examines every major aspect of Alzheimer disease at a time when there has been no scholarly research volume on the subject published in the last 3-5 years. This edition includes expanded coverage of the cellular-level exploration of related dementing disorders, with in-depth presentation of prion diseases, Pick's disease, fronto-temporal disorders, transgenic models, and biochemistry of presenilins.
The Genetics of Alzheimer’s Disease.- APP Biology, Processing and Function.- The Biology of the Presenilin Complexes.- ?-secretase: Physiological Role and Target Validation.- Cognitive Impairment in Transgenic A? and Tau Models of Alzheimer’s Disease.- Cholesterol and ?-Amyloid.- A? Structure and Aggregation.- Signaling Mechanisms that Mediate A? Induced Neuronal Dysfunction.- Beta Amyloid and Excitatory Synapses.- A? Degradation.- Role of A ? Transport and Clearance in the Pathogenesis and Treatment of Alzheimer’s Disease.- Tau Gene Mutations in FTDP-17 Syndromes.- Animal Models of Tauopathy.- Tau and Axonal Transport.- Growth Factors in Alzheimer’s Disease.
| Zusatzinfo | 5 Illustrations, color; 19 Illustrations, black and white; X, 286 p. 24 illus., 5 illus. in color. |
|---|---|
| Verlagsort | New York, NY |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Geriatrie |
| Medizin / Pharmazie ► Medizinische Fachgebiete ► Neurologie | |
| Medizin / Pharmazie ► Studium | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| ISBN-10 | 0-387-35134-5 / 0387351345 |
| ISBN-13 | 978-0-387-35134-6 / 9780387351346 |
| Zustand | Neuware |
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