Apoptosis, Cell Signaling, and Human Diseases

Molecular Mechanisms, Volume 2

Buch | Hardcover

402 Seiten

2007
Humana Press Inc. (Verlag)
978-1-58829-882-9 (ISBN)

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Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 & 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology.

Volume 1 is divided into two sections: "Malignant Transformation and Metastasis" and "Molecular Basis of Disease Therapy." Volume 2 follows a similar structure and is divided into sections entitled "Kinases and Phosphate" and "Molecular Basis of Cell Death." All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.

Kinases and Phosphatases.- Significance of Protein Kinase A in Cancer.- Protein Kinase C and Apoptosis.- The Role of Phosphoinositide 3-Kinase-Akt Signaling in Virus Infection.- Cyclin-Dependent Kinase 5.- Critical Roles of the Raf/MEK/ERK Pathway in Apoptosis and Drug Resistance.- MAPK Signaling in Human Diseases.- Serine/Threonine Protein Phosphatases in Apoptosis.- Urokinase/Urokinase Receptor-Mediated Signaling in Cancer.- Molecular Basis of Cell Death.- Signaling Pathways That Protect the Heart Against Apoptosis Induced by Ischemia and Reperfusion.- Cyclooxygenase-2 Gene Expression.- Death Receptors.- DNA Damage-Dependent Apoptosis.- The Role of Proteasome in Apoptosis.- Apoptosis Induction in T Lymphocytes by HIV.- Inhibitor of Apoptosis Proteins and Caspases.- Intracellular Pathways Involved in DNA Damage and Repair to Neuronal Apoptosis.- The Biology of Caspases.- Apoptosis and Human Diseases: Molecular Mechanisms.

Zusatzinfo	1 Illustrations, color; 48 Illustrations, black and white; XVI, 402 p. 49 illus., 1 illus. in color.
Verlagsort	Totowa, NJ
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
	Naturwissenschaften ► Biologie ► Mikrobiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
ISBN-10	1-58829-882-5 / 1588298825
ISBN-13	978-1-58829-882-9 / 9781588298829
Zustand	Neuware