A Statistical Approach to Genetic Epidemiology
Wiley-VCH (Verlag)
978-3-527-31252-8 (ISBN)
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After providing a concise introduction to genetic fundamentals, the authors explain both linkage analysis and association analysis in detail. The textbook features more than 100 problems and solutions.
With a foreword by Robert C. Elston, Director, Division of Genetic and Molecular Epidemiology at the Case Western Reserve University, Cleveland, Ohio.
After studying statistics and mathematics at the University of Munich and obtaining his doctoral degree from the University of Dortmund, Andreas Ziegler received the Johann-Peter-Süßmilch-Medal of the German Association for Medical Informatics, Biometry and Epidemiology for his post-doctoral work on "Model Free Linkage Analysis of Quantitative Traits" in 1999. In 2004, he was one of the recipients of the Fritz-Linder-Forum-Award from the German Association for Surgery. Andreas Ziegler is head of the Institute for Medical Biometry and Statistics at the University Clinic Schleswig-Holstein in Lübeck, an acknowledged center of excellence for genetic epidemiological methods. Currently he is President of the German Region of the International Biometric Society. Inke R. König studied psychology at the universities of Marburg (Germany) as a scholar of the German National Academic Foundation and Dundee (Scotland) with a grant from the German Academic Exchange Service (DAAD). She has done research work at the Institute of Medical Biometry and Epidemiology in Marburg and since 2001 at the Institute of Medical Biometry and Statistics in Lübeck. In 2004, she became vice director of the latter and also received the Fritz-Linder-Forum-Award from the German Association for Surgery. Besides holding the certificate "Biometrics in Medicine", she has collected teaching experience since 1998 as a lecturer for biomathematics, behavioural genetics, clinical epidemiology, genetic epidemiology, and evidence-based medicine.
INTRODUCTORY GENETICS
Molecular Genetics
Formal Genetics
Genetic Markers
Data Quality
LINKAGE ANALYSIS
Genetic Map Distances
Model Based Linkage Analysis
Model Free Linkage Analysis for Dichotomous Traits
Model Free Linkage Analysis for Quantitative Traits
ASSOCIATION ANALYSIS
Fundamental Concepts
Case-Control Association Analysis
Family-Based Association Analysis
Haplotypes in Association Analyses
Appendix: Algorithms Used in Linkage Analyses
| Sprache | englisch |
|---|---|
| Maße | 170 x 240 mm |
| Gewicht | 824 g |
| Einbandart | gebunden |
| Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
| Schlagworte | Biostatistik • Epidemiologie • Genetik |
| ISBN-10 | 3-527-31252-8 / 3527312528 |
| ISBN-13 | 978-3-527-31252-8 / 9783527312528 |
| Zustand | Neuware |
| Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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