Mechanics of Motor Proteins and the Cytoskeleton

Jonathon Howard (Autor)

Buch | Softcover

384 Seiten

2005
Oxford University Press Inc (Verlag)
978-0-87893-333-4 (ISBN)

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Mechanics of Motor Proteins and the Cytoskeleton provides a physical foundation for molecular mechanics. Part I explains how small particles like proteins respond to mechanical, thermal, and chemical forces, Part II focuses on cytoskeletal filaments, and Part III focuses on motor proteins. The treatments are unified in the respect that they are organized around principles rather than proteins: chapters are centred on topics such as structure, chemistry, and mechanics, and different filaments or motors are discussed together.

JONATHON HOWARD is Professor of Physiology and Biophysics at the University of Washington in Seattle, USA.

Preface.- Introduction.- PART I: PHYSICAL PRINCIPLES.- Mechanical Forces.- Mass, Stiffness, and Damping of Proteins.- Thermal Forces and Diffusion.- Chemical Forces.- Polymer Mechanics.- PART II: CYTOSKELETON.- Structures of Cytoskeletal Filaments.- Mechanics of the Cytoskeleton.- Polymerization of Cytoskeletal Filaments.- Force Generation by Cytoskeletal Filaments.- Active Polymerization.- PART III: MOTOR PROTEINS.- Structures of Motor Proteins.- Speeds of Motors.- ATP Hydrolysis.- Steps and Forces.- Motility Models: From Crossbridges to Motion.- Afterword.- Appendix.- Bibliography.- Index.

Erscheint lt. Verlag	6.12.2005
Reihe/Serie	WH Freeman
Zusatzinfo	384 p.
Verlagsort	New York
Sprache	englisch
Maße	177 x 235 mm
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
Themenwelt	Naturwissenschaften ► Biologie ► Biochemie
ISBN-10	0-87893-333-6 / 0878933336
ISBN-13	978-0-87893-333-4 / 9780878933334
Zustand	Neuware