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Substance P

From Pain to Cancer

Robert Vink (Herausgeber)

Buch | Softcover
550 Seiten
2024
Academic Press Inc (Verlag)
978-0-443-22194-1 (ISBN)
CHF 279,95 inkl. MwSt
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Substance P: From Pain to Cancer, a volume in the Molecular Mediators in Health and Disease: How Cells Communicate series, provides a complete discussion of substance P biology, its role in normal physiology and a variety of diseases.

The volume provides an introduction to substance P and its pharmacology, followed by exploring its role across the human body including cardiovascular function, micturition, learning and memory, emesis, respiration and sleep. It then discusses the critical role of substance P in several disease states including acute brain injury, neurodegeneration, seizures, depression and anxiety, cancer, musculoskeletal disorders, and viral infection, including COVID-19. The book closes with a look towards future perspectives for substance P.

Substance P: From Pain to Cancer is an ideal reference for researchers across the life sciences interested in understanding the role of this multi-functioning mediator and its biological significance.

Robert Vink is an Emeritus Professor at the University of South Australia and is currently Chair of the Board for Connectivity: Traumatic Brain Injury Australia. He was previously appointed as the Professor and Chair of Neurosurgical Research and Head of School, Medical Sciences at the University of Adelaide, Australia. Throughout his time as a teaching/research academic he led a highly productive research group and maintained an extensive publication output. He is the author of over 260 articles and book chapters. He has supervised more than 30 graduate research students, many of whom now hold significant academic and other positions throughout Australia and internationally. He is known internationally for his work in traumatic brain injury and has received numerous prestigious awards and appointments related to this. He currently provides research consulting services to universities and the pharmaceutical industry.

1. The synthesis, release, and binding of substance P Brendan A. Hilliard, Robert Vink, and Mary F. Barbe 2. Distribution of substance P receptors in mammals Honoo Satake, Akira Shiraishi, and Tsuyoshi Kawada 3. Substance P in nonmammalian biology: Evolutionarily conserved tachykinin signaling Dick R. Nassel 4. Methodological foundations of substance P detection Nuray Erin 5. Substance P receptor antagonists Francisco D. Rodrıguez and Rafael Covenas 6. Substance P in the cardiovascular system Magdalena Chottova Dvorakova and Shashank Pandey 7. Substance P in lower urinary tract function and dysfunction Mitsuharu Yoshiyama 8. Role of the substance P in learning and memory Natalia Favila and Paul G. Overton 9. Substance P in nausea and vomiting Paul L.R. Andrews, John A. Rudd, and Gareth J. Sanger 10. Substance P in the central control of respiration Nicholas J. Burgraff and Jan-Marino Ramirez 11. Substance P in bone metabolism Tanja Niedermair and Susanne Grassel 12. Life without substance P: The naked mole rat Aishi Zhao, Jiwon Lee, Weronika Gryszkiewicz, and Thomas J. Park 13. Substance P in inflammation Sophie E. Sipprell and Ian Marriott 14. Substance P in oxidative stress Seyed Isaac Hashemy and Safieh Ebrahimi 15. Substance P in pain Robert Vink 16. Substance P in cancer Miguel Munoz, Marisa Rosso, Riffat Mehboob, and Francisco Esteban 17. Substance P in cardiac dysfunction Scott P. Levick and Alexander Widiapradja 18. Substance P in neurotrauma Rebecca George, Justin Krieg, and Frances Corrigan 19. Substance P in stroke Annabel Sorby-Adams 20. Substance P in Alzheimer’s and Parkinson’s disease Severini Cinzia 21. Substance P receptor antagonists for major depressive disorder Nadia M.J. Rupniak and Mark S. Kramer 22 From a putative antidepressant to a validated mouse model of ADHD via NK1 receptors S.C. Stanford 23. Substance P in stress and anxiety Karl Ebner and Nicolas Singewald 24. Substance P-neurokinin 1 receptor pathway in musculoskeletal disorders Brendan A. Hilliard and Mary F. Barbe 25. Substance P and sudden infant death syndrome (SIDS) F. Bright, Robert Vink, and R.W. Byard 26. Immunobiology and pharmacology of neuropeptide substance P Ehsan Aslam, Asina Gijasi, Caroline Perner, Rob van Wijk, Anne-Grete Martson, Gerard J.P. van Westen, Ilze Bot, Laura H. Heitman, and Alireza Mashaghi 27. Substance P in viral diseases—Especially coronavirus disease Riffat Mehboob, Mariam Hashim, and Miguel Munoz 28. Substance P: Perspectives and future directions Robert Vink

Erscheinungsdatum
Reihe/Serie Molecular Mediators in Health and Disease: How Cells Communicate
Verlagsort San Diego
Sprache englisch
Maße 191 x 235 mm
Gewicht 450 g
Themenwelt Naturwissenschaften Biologie Zellbiologie
ISBN-10 0-443-22194-4 / 0443221944
ISBN-13 978-0-443-22194-1 / 9780443221941
Zustand Neuware
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