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Chemokine Biology: Basic Research and Clinical Application -

Chemokine Biology: Basic Research and Clinical Application

Media-Kombination
224 Seiten
2007 | 2007
Springer Basel
978-3-7643-7307-8 (ISBN)
CHF 224,65 inkl. MwSt
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Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV. Volume 1 of this two-volume set discusses the immunobiology of chemokines. It is divided into two parts: a) cellular targets in innate and adaptive immunity, and b) effector cell traffic-unrelated functions. Together with volume 2, which discusses the pathophysiology of chemokines, both volumes give a comprehensive overview of chemokine biology.

Traffic of T lymphocytes.- Lymphocyte homing to peripheral epithelial tissues.- Chemokine biology of NK-cells and gd T cells.- Dendritic cell traffic control by chemokines.- Chemokine receptor-mediated signal transduction.- Chemokines in leukocyte transendothelial migration.- Natural chemokine antagonism and synergism.- Crosstalk between chemokine, opioid and vanilloid receptors.- Antimicrobial and related activities of chemokines.- Virus-encoded chemokine modulators as novel anti-inflammatory reagents.- Chemokine receptors in tissue cells and angiogenesis.

Erscheint lt. Verlag 23.4.2007
Reihe/Serie Progress in Inflammation Research
Zusatzinfo 224 p. 2 volume-set.
Verlagsort Basel
Sprache englisch
Gewicht 640 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Studium Querschnittsbereiche Infektiologie / Immunologie
Naturwissenschaften Biologie Zellbiologie
Schlagworte Animal disease models • Cell Biology • Drug targets • homeostasis • Immunbiologie • Zellbiologie
ISBN-10 3-7643-7307-5 / 3764373075
ISBN-13 978-3-7643-7307-8 / 9783764373078
Zustand Neuware
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