Metabolic Network Reconstruction and Modeling (eBook)

Methods and Protocols

Marco Fondi (Herausgeber)

eBook Download: EPUB

2017
Springer New York (Verlag)
978-1-4939-7528-0 (ISBN)

Infos

This volume looks at the latest methodologies used to study cellular metabolism with in silico approaches. The chapters in this book are divided into 3 parts: part I discusses tools and methods used for metabolic reconstructions and basic constraint-based metabolic modeling (CBMM); Part II explores protocols for the generation of experimental data for metabolic reconstruction and modeling, including transcriptomics, proteomics, and mutant generations; and Part III cover advanced techniques for quantitative modeling of cellular metabolism, including dynamic Flux Balance Analysis and multi-objective optimization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting-edge and thorough, MetabolicNetwork Reconstruction and Modeling: Methods and Protocols is a valuable resource for qualified investigators studying cellular metabolism, and novice researchers who want to start working with CBMM.

Produkt-Details

• Erscheint lt. Verlag: 8.12.2017
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Zellbiologie
• ISBN-10: 1-4939-7528-5 / 1493975285
• ISBN-13: 978-1-4939-7528-0 / 9781493975280