Transportome Malfunction in the Cancer Spectrum

Ion Transport in Tumor Biology

Christian Stock, Luis A. Pardo (Herausgeber)

Buch | Softcover

IX, 427 Seiten

2022 | 1st ed. 2021
Springer International Publishing (Verlag)
978-3-030-90922-2 (ISBN)

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This is the first of three volumes in the "Ion Channels & Transporters in Tumor Biology" collection, which discusses the function of ion transport proteins in cellular and systemic homeostasis. The authors highlight the role of the so-called transportome, which is defined by the entirety of ion transporters and ion channels. Thereby, readers will get a better understanding of the impact dysregulated ion transport has on the whole spectrum of cancer types. Cancers display deficiencies in several, sometimes interdependent members of the transportome.
Clinicians will be interested in the fact that controlled expression of ion transport proteins dramatically impacts the life span of cancer patients, as shown in recent studies. These observations offer a promising outlook for biomedical scientists, as members of the transportome could be the tumor markers of tomorrow - both for diagnostic and therapeutic purposes.
As part of a three-volume collection, this book will fascinate members of the active research community, as well as clinicians from the cancer field.

Effects of the Tumor Environment on Ion Channels: Implication for Breast Cancer Progression.- Ion Channel Profiling in Prostate Cancer: Toward Cell Population-Specific Screening.- Ion channels in Lung Cancer.- Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer.- Transportome Malfunctions and the Hallmarks of Pancreatic Cancer.- How Dysregulated Ion Channels and Transporters Take a Hand in Esophageal, Liver, and Colorectal Cancer.- Ion Channels in Glioma Malignancy.- Membrane Transporters and Channels in Melanoma.- Ion Channel Dysregulation in Head and Neck Cancers: Perspectives for Clinical Application.

Erscheinungsdatum	20.12.2022
Reihe/Serie	Reviews of Physiology, Biochemistry and Pharmacology
Zusatzinfo	IX, 427 p. 50 illus., 25 illus. in color.
Verlagsort	Cham
Sprache	englisch
Maße	155 x 235 mm
Gewicht	662 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie ► Biochemie
Schlagworte	aggressive cancer • ion channels • Kaplan-Meier-Plot • Malignancy • Metastasis
ISBN-10	3-030-90922-0 / 3030909220
ISBN-13	978-3-030-90922-2 / 9783030909222
Zustand	Neuware