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The Trajectory of Discovery - Mark P. Khurana

The Trajectory of Discovery

What Determines the Rate and Direction of Medical Progress?

(Autor)

Buch | Softcover
192 Seiten
2023
Cambridge University Press (Verlag)
978-1-009-35443-1 (ISBN)
CHF 52,35 inkl. MwSt
Exploring the forces that determine the rate and direction of medical progress, this book brings together the worlds of scientific policy, economics, sociology, and innovation to describe the medical research landscape. Covers how issues, including incentive structures and lack of novelty in drug development, influence and impede progress.
Medical research works in trajectories. Scientists and researchers must choose to pursue certain scientific pathways and omit others, limited by resources, attention, and time. The trajectory of medical progress is therefore characterized by two crucial characteristics: rate and direction. These two components form the foundation for this book - what are the forces that determine the rate and direction of progress in medicine? This book brings together the worlds of scientific policy, economics, sociology, philosophy, and innovation to describe why the world of medical research looks the way it does. The book also addresses fundamental contemporary issues in medicine, how they influence progress, and how we might improve medical research going forward. The contemporary issues discussed include: flawed incentive structures, a concentration of power and resources among few actors and disease groups, the potential distortionary effects of lobbying by different scientific actors, and missing novelty in drug development.

Mark P. Khurana is a Medical Doctor and Epidemiologist. He is a Research Fellow at the University of Copenhagen, primarily in Infectious Disease Epidemiology. He is Host and Creator for the 'Untold Health' podcast which explores topics within the field of health which are significant but overlooked.

Part I. Incentives, Context and Capital: 1. Citations as currency; 2. Hacking statistics; 3. The allure of prizes; 4. Streetlight effects; 5. Patented and regulated progress; 6. Teams and diversity; Part II. The Financial Determinants of Discovery: 7. The research marketplace; 8. Winners take all; 9. Public service; 10. The medici model; 11. The goldilocks zone; 12. Kindling creativity; Part III. Bending the Arc: 13. Lobbying for change; 14. Scientific elasticity; 15. Death of a star // new kids on the block; 16. Great emergencies; 17. Fraudulent findings; 18. Serendipity; 19. Converging paths; Part IV. Reflecting on the Trajectory: 20. Civic engagement; 21. Uncertainty; 22. Commercialization and power; 23. Morality and progress.

Erscheinungsdatum
Zusatzinfo Worked examples or Exercises
Verlagsort Cambridge
Sprache englisch
Maße 155 x 234 mm
Gewicht 270 g
Themenwelt Medizin / Pharmazie Allgemeines / Lexika
Studium 1. Studienabschnitt (Vorklinik) Med. Psychologie / Soziologie
Naturwissenschaften
ISBN-10 1-009-35443-4 / 1009354434
ISBN-13 978-1-009-35443-1 / 9781009354431
Zustand Neuware
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