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Normal Testicular Descent and the Aetiology of Cryptorchidism

John M. Hutson, Masaru Terada, Baiyun Zhou, Martyn P.L. Williams (Autoren)

Buch | Softcover

V, 56 Seiten

1995 | 1. Softcover reprint of the original 1st ed. 1996
Springer Berlin (Verlag)
978-3-540-60283-5 (ISBN)

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This review describes recent research into the cause of testicular descent and discusses two controversial theories on the mechanism. New animal models of cryptorchidism are described which shed light on the possible aetiology. A brief summary is given of current management, highlighting the controversies of timing of surgery, use of hormone therapy and congenital versus 'acquired' undescended testes. New information about germ cell development in the postnatal testis is changing the way we view treatment and the ultimate prognosis.

1 Introduction.- 2 Normal Testicular Descent.- 2.1 Two-Stage Hypothesis.- 2.2 Role of Müllerian Inhibiting Substance/Anti-Müllerian Hormone.- 2.3 Genitofemoral Nerve Hypothesis.- 2.4 Role of Calcitonin Gene-Related Peptide.- 2.5 Hypothesis to Explain Normal Testicular Descent.- 3 Cryptorchidism.- 3.1 Animal Models.- 3.2 Hypotheses of Aetiology.- 3.3 Recognizable Causes of Cryptorchidism.- 3.4 Congenital vs Acquired Cryptorchidism.- 3.5 Effects of Cryptorchidism.- 4 Management of Cryptorchidism.- 4.1 Rationale for Treatment and Its Timing.- 4.2 Surgical Treatment.- 4.3 Hormonal Treatment.- 4.4 Possible New Approaches to Treatment.- 5 Conclusions.- 6 References.- 7 Subject Index.

Erscheint lt. Verlag	12.12.1995
Reihe/Serie	Advances in Anatomy, Embryology and Cell Biology
Zusatzinfo	V, 56 p. 13 illus.
Verlagsort	Berlin
Sprache	englisch
Maße	155 x 235 mm
Gewicht	140 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Urologie
	Studium ► 1. Studienabschnitt (Vorklinik) ► Anatomie / Neuroanatomie
	Naturwissenschaften ► Biologie ► Biochemie
Schlagworte	Cell • Cryptorchidism • Development • Hodenhochstand • Hormone • Hormone Therapy • Krypptorchismus • Surgery • Testicular Descent • Testis • undescended testis
ISBN-10	3-540-60283-6 / 3540602836
ISBN-13	978-3-540-60283-5 / 9783540602835
Zustand	Neuware