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Biomarkers in Trauma, Injury and Critical Care

Media-Kombination
1st ed. 2025
Springer International Publishing AG
978-3-031-07396-0 (ISBN)
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This handbook systematically presents biomarkers of traumatic injuries To name a few, traumatic brain injury, liver injury, burn severity, muscle heart damage and acute inflammation in polytrauma and their biomarker detection are discussed.Biomarkers and the method used in Critical Care and Critically III Patients are depicted and so are Biomarkers in Trauma and in special conditions. Special biomarker components are elucidated and models for modelling Trauma in research are shown.



This systematic handbook provides an excellent resource for researchers and specialists in trauma research and treatment, as well as clinicians and medical doctors that wish to gain a thorough overview on diverse injuries, trauma and their methods of detection.

Rajkumar Rajendram, PhD is Locum Consultant in General Medicine at John Radcliffe Hospital, Oxford, and Visiting Research Fellow in the Nutritional Sciences Research Division at King's College London, United Kingdom. Dr Rajendram graduated in 2001 with a distinction from Guy's, King's and St. Thomas Medical School, in London. This was followed by training in general medicine and intensive care in Oxford. He attained membership of the Royal College of Physicians (MRCP) in 2004. Dr Rajendram went on to train in anaesthesia and intensive care in the Central School of Anaesthesia, London Deanery, and became a fellow of the Royal College of Anaesthetists (FRCA) in 2009. He has completed higher training in regional anaesthesia, pain medicine, and intensive care, and devoted significant time and effort into nutritional science research. He has published over 50 textbook chapters, review articles, peer-reviewed htttttapers, and abstracts. Victor R. Preedy is a professor in the School of Medicine, King's College London. He directs studies regarding pathology, health, nutrition and toxicity. Professor Preedy graduated in 1974 from the University of Aston with a Combined Honours Degree in Biology and Physiology with Pharmacology. He gained his Ph.D. in 1981, in the field of nutrition and metabolism, from the London School of Hygiene and Tropical Medicine, University of London. Professor Preedy was elected as a Fellow to the Royal College of Pathologists in 2000. Vinood B. Patel, BSc, PhD, FRSC, is a Senior Lecturer in Clinical Biochemistry at the University of Westminster. Dr Patel graduated from the University of Portsmouth with a degree in Pharmacology and completed his PhD in protein metabolism from King's College London in 1997. His postdoctoral work was carried out at Wake Forest University Baptist Medical School studying structural-functional alterations to mitochondrial ribosomes, where he developed novel techniques to characterize their biophysical properties. In 2014, he was elected as a Fellow to The Royal Society of Chemistry. Dr Patel is a nationally and internationally recognized researcher and was involved in several NIH-funded biomedical grants related to disease. Dr Patel has edited biomedical books in the area of diet, nutrition and health prevention. He has published over 150 articles.

Biomarkers and outcomes: the example of traumatic brain injury.- Biomarkers in neurological injury: fibrinogen and beyond.- Biomarkers for liver injury: micro RNAS and beyond.- Biomarkers in muscle injury: proteomic and beyond.- Biomarkers in lung injury:.- Biomarkers and penetrating thoracic trauma.- Biomarkers in renal injury.- Biomarkers of heart muscle damage and injury: mRNA expression and beyond.- Biomarkers of burn severity.- Biomarkers and prognosis in sepsis: muscle mass and beyond.- Biomarkers of acute inflammation in polytrauma.- Electrolytes in critical care as a biomarker.- Critical care and 5'-Aminolevulinate synthase 2 (ALAS2) expression as a biomarker.- miRNAs as biomarkers of critically Ill patients.- C-Reactive protein and implications to the Neonatal Intensive Care Unit.- 129Xe magnetic resonance imaging (MRI) as a biomarker and implications for critical care.- Gas imaging of aeration and fractional ventilation as a biomarker in critical care.- Circulating PD-1/2B4 CD8+ T-cells patterns as biomarkers and the ICU.- Collagen and fibrotic biomarkers in critical care.- Biomarker mortality prediction model for sepsis in critical care: parsimonious modelling and beyond.- Acute kidney injury in critical care and biomarkers.- Platelet Function Assays in trauma.- Coagulation tests and fibrinogen concentrate in trauma.- Biomarkers and the time window-in trauma patients.- Inflammatory biomarkers in animal model of brain Injury

Reihe/Serie Biomarkers in Disease: Methods, Discoveries and Applications
Zusatzinfo Approx. 1100 p. Print + eReference.
Verlagsort Cham
Sprache englisch
Maße 155 x 235 mm
Themenwelt Medizin / Pharmazie
Naturwissenschaften Biologie Zellbiologie
ISBN-10 3-031-07396-7 / 3031073967
ISBN-13 978-3-031-07396-0 / 9783031073960
Zustand Neuware
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