Lipid Metabolism in Tumor Immunity

Buch | Softcover

211 Seiten

2022 | 1st ed. 2021
Springer Verlag, Singapore
978-981-336-787-6 (ISBN)

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This book focuses on lipid metabolism in tumor immunity, covering the application of lipidomics in tumor immunity and all aspects of lipid metabolism in tumor microenvironment. During the progression of tumors, tumor cells and immune cells interact in a dynamic microenvironment. Targeting the immune system has a high potential for treating cancer. However, due to the high heterogeneity of the tumor microenvironment, only a small percentage of patients experience such clinical benefits of tumor immunotherapy. Therefore, understanding the tumor microenvironment is crucial for tumor immunity. Recently, lipid metabolism is an emerging research direction and contributes to cell survival and biofunctions in tumor microenvironment, which is of great interest and significance to be elucidated. This book provides the doctors, researchers, and scientists with a cutting-edge overview of the lipid metabolism and its role in tumor immunity. It also yields benefits for pharmaceutical companies regarding drug discovery.

Dr. Yongsheng Li now is Professor and Deputy Director of Clinical Medicine Research Center in Xinqiao Hospital, Army Medical University in Chongqing, China. He obtained his M.D. from Yunyang Medical College of Tongji Medical University in 2005 and his Ph.D. from Huazhong University of Science and Technology in 2009, respectively. After that, he was Research Fellow in Beth Israel Deaconess Medical Center. Later, from 2010 to 2015, he continued his post-doctoral training in Brigham and Women’s Hospital in the USA as research fellow. In 2016, he moved back to China and joined Army Medical University (A.K.A. Third Military Medical University) and the same year, he was selected in the "Youth 1000 Talent Plan" of China.

1. Introduction: Introduction of lipids, lipid metabolism and tumor immunity.- 2. ipid metabolism and lipidomics.- 3. Applications of lipidomics in tumour immunity.-4. Overview: Lipid metabolism in tumour microenvironment.- 5. Lipid metabolism in cancer cells.- 6. Lipid metabolism in tumour-associated NK.- 7. Lipid metabolism in tumour-associated macrophages.- 8. Lipid metabolism in tumour-associated MDSCs.- 9. Lipid metabolism in tumour-associated fibroblasts.- 10. Lipid metabolism in tumour-associated B cells.- 11. Lipid metabolism in tumour-infiltrating T cells.- 12. Lipid metabolism and angiogenesis.- 13. Lipid metabolism and tumor antigen-presenting.- 14. Lipid metabolism and immune checkpoints.

Erscheinungsdatum	23.03.2022
Reihe/Serie	Advances in Experimental Medicine and Biology ; 1316
Zusatzinfo	23 Illustrations, color; 1 Illustrations, black and white; XI, 211 p. 24 illus., 23 illus. in color.
Verlagsort	Singapore
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Mathematik / Informatik ► Informatik ► Theorie / Studium
	Informatik ► Weitere Themen ► Bioinformatik
	Medizin / Pharmazie ► Medizinische Fachgebiete ► Onkologie
	Studium ► Querschnittsbereiche ► Infektiologie / Immunologie
	Naturwissenschaften ► Biologie ► Zellbiologie
Schlagworte	Cancer • immune checkpoints • Lipid metabolism • Lipidomics • Metabolomics • tumor immunity • Tumor microenvironment (TME)
ISBN-10	981-336-787-3 / 9813367873
ISBN-13	978-981-336-787-6 / 9789813367876
Zustand	Neuware