Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects

Sangita Das, Sabu Thomas, Partha Pratim Das (Herausgeber)

Buch | Softcover

764 Seiten

2022
Elsevier - Health Sciences Division (Verlag)
978-0-323-90553-4 (ISBN)

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Sensing of Deadly Toxic Chemical Warfare Agents, Nerve Agent Simulants, and their Toxicological Aspects provides a general overview of the development and performance of different novel molecular frameworks as potent vehicles for sensing Chemical Weapons (CWs). The chapters are contributed by leading researchers in the areas of materials science, medical science, chemical science, and nanotechnology from industries, academics, government and private research institutions across the globe. It covers cover topics such as inorganic nanocomposites, hyperbranched polymers, and graphene heterojunctions for effective sensing of CW agents. This book is a highly valuable reference source for graduates, post-graduates, and research scholars primarily in the fields of materials science, medicinal chemistry, organic chemistry, and nanoscience and nanotechnology. In addition, almost all analytical techniques will be discussed, making this a first-rate reference for professors, students, and scientists in many industries.

Dr. Sangita Das is working as Newton International Fellow at Durham University, England, United Kingdom. She also works as a visiting professor in the Department of Energy Science in Mahatma Gandhi University, Kerala, India. She received her B. Sc. degree with honors in chemistry in 2008 from the University of Calcutta, Kolkata, West Bengal, India. She obtained her M. Sc. degree in chemistry with organic specialization in 2010 from the same university. She had qualified the all India (CSIR–JRF) NET, and then she joined “The Goswami Group, Department of Chemistry, IIEST for her doctoral work under the supervision of Prof. Shyamaprosad Goswami. She got Ph.D. in 2016. Her areas of research interest include molecular recognition; design of fluorescence chemosensors; and characterization of fluorescence probe (detection of metal ions, anions, reactive oxygen species, nerve gas, and other environmentally hazardous species, etc.); aggregation-induced emission dyes and solid-state emitters, and synthesis of compounds with antidiabetic activity. She is now working as a Newton International Fellow in the United Kingdom. Her current research activities include the development of compounds as HDAC inhibitors, experimental and theoretical investigations of electronic structure of transition metal complexes with redox noninnocent ligands, and computational chemistry (DFT, TDDFT calculations). Prof. Sabu Thomas is a Professor of Polymer Science and Engineering and the Director of the School of Energy Materials at Mahatma Gandhi University, India. Additionally, he is the Chairman of the Trivandrum Engineering Science & Technology Research Park (TrEST Research Park) in Thiruvananthapuram, India. He is the founder director of the International and Inter-university Centre for Nanoscience and Nanotechnology at Mahatma Gandhi University and the former Vice-Chancellor of the same institution. Prof. Thomas is internationally recognized for his contributions to polymer science and engineering, with his research interests encompassing polymer nanocomposites, elastomers, polymer blends, interpenetrating polymer networks, polymer membranes, green composites, nanocomposites, nanomedicine, and green nanotechnology. His groundbreaking inventions in polymer nanocomposites, polymer blends, green bionanotechnology, and nano-biomedical sciences have significantly advanced the development of new materials for the automotive, space, housing, and biomedical fields. Dr. Thomas has been conferred with Honoris Causa (DSc) by the University of South Brittany, France. Dr. Partha Pratim Das is presently working as a postdoctoral researcher in Seoul National University, South Korea. He previously worked in the Institute of High-Pressure Mineral Physics and Chemistry, Yonsei University, Seoul, South Korea, as a postdoctoral researcher. He has completed both the B.Sc. (2008) and M.Sc. (2010) in chemistry from Calcutta University, India. He has received Ph.D. in science (chemistry) in 2016 from Jadavpur University, India. His working laboratories during Ph.D. are CSIR-CGCRI, Kolkata, and CSIR-NCL, Pune, India. His research area is focused on nanotechnology, synthesis, and structure–properties correlation studies of different multifunctional nanomaterials under various conditions for mainly clean and sustainable energy and environmental applications. He has published several high-impact papers in peer-reviewed journals. Moreover, his research works have been acclaimed in many national and international conferences and journal societies.

Introduction

1. Chemical warfare agents: An outlook on past and present technologies 2. Metal-Organic-Framework Composite based rapid Self-Detoxifying Smart Textile Filters for Chemical-Warfare Agents 3. Plasmonic Nanosensors for Chemical Warfare Agents 4. Quantification of DCP (diethylchlorophosphate) for the recognition of organophosphorous chemical warfare agents 5. Advances in gold nanoparticles for optical detection of nerve agents 6. Functionalized two-dimensional photonic crystals for the detection of chemical warfare agents 7. Optically advanced Carbon dots for sensing of harmful toxins 8. Nano Materials in Organophosphate Sensing: Present and Future Perspective 9. Smart hydrogel nanostructured sensor for detection of organophosphorus chemical warfare nerve agents 10. Graphene based nanocomposites for detection of chemical messengers in nervous system 11. Aptamer based approaches for sensing harmful synthetic and natural toxins 12. MOFs derived nanoarchitectures for the detection of phenolic compounds 13. Sensing of Phenol and Chlorophenols using Carbon Nanotubes Modified Glassy Carbon Electrode 14. Nanotubes tethered laccase biosensor for sensing of chlorophenol substances 15. Use of organic compounds as Medical Products for the therapeutic treatment exposed to CW's agents 16. An assessment of Chemical Warfare Agents in soils: Detection, Distribution and Ecotoxicology 17. Assessment of the impact of chemical weapons disposal in the ocean according to international conventions 18. Chemical Warfare: Unprecedented Environmental Threat 19. Clinical Symptoms of Chemical Warfare Agents Toxicity including Mustards, Halogenated Oximes, Arsenicals, Toxins Poisoning 20. Advances targeted therapy in toxicology and medical treatment of chemical warfare nerve agents 21. The reversible inhibitors of acetylcholinestrerase as pre-treatment options against nerve agents intoxications 22. Paraoxonase 1 as a potential prophylactic countermeasure against nerve agent poisoning 23. Potential Alternative treatments and Routes of Administrations: Chemical Warfare Agents Poisoning 24. Therapeutic Treatment of Nerve Agent toxicity 25. Carbon-nanomaterial modified molecularly imprinted polymers for the sensing of Organophosphorus simulants 26. Carbon-nanomaterial modified recognition platforms for the sensing of organophosphorous simulants 27. Graphene-based nanocomposites for electrochemical sensing of Organophosphate triesters 28. Synthesis of simulants of nerve agents for the assays of AChE inhibition 29. Toxicological and Pharmacological Aspects of Organophosphorus Nerve Agents

Erscheinungsdatum	26.09.2022
Zusatzinfo	180 illustrations (10 in full color); Illustrations
Verlagsort	Philadelphia
Sprache	englisch
Maße	191 x 235 mm
Gewicht	1540 g
Themenwelt	Naturwissenschaften ► Chemie ► Analytische Chemie
ISBN-10	0-323-90553-6 / 0323905536
ISBN-13	978-0-323-90553-4 / 9780323905534
Zustand	Neuware