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Fasciolosis (eBook)

John Pius Dalton (Herausgeber)

eBook Download: EPUB
2021 | 2. Auflage
504 Seiten
CABI (Verlag)
978-1-78924-618-6 (ISBN)

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Fasciolosis is a major infection of livestock, causing huge losses to the agricultural community and affecting human health. This fully updated new edition covers parasite biology and development, immunology, diagnosis, vaccines, and emergence of drug resistance, as well as new advances in genomics, transcriptomics, proteomics and glycomics.
Fasciolosis is a major global infection of livestock causing both huge losses to the agricultural community and affecting human health as a food-borne disease. Fully updated throughout, this new edition continues to cover the life cycle, biology, and development of the parasite; clinical pathology, immunology, diagnosis and vaccine development; and emergence, cause and mechanisms of drug resistance. It reviews the temperate liver fluke Fasciola hepatica, together with molecular, biochemical, control, and epidemiologial aspects of the tropical liver fluke F. gigantica.

Many fundamental advances have taken place in the last two decades, but of particular importance has been the mapping of the draft genome of Fasciola. In addition, comprehensive advances in transcriptomics, proteomics and glycomics have been made, and the book therefore pays particular attention to these developments with the addition of brand-new chapters. Also covering the impact these parasites have had on the global human population, their distribution and their ecology, this book provides a comprehensive and accessible resource for scientists, researchers and students of medical and veterinary parasitology.

Professor John Dalton graduated from University College Dublin with a PhD in Molecular Parasitology, before becoming a Postdoctoral Research Fellow working on schistosomes at the Johns Hopkins School of Medicine, then malaria at the National Institute of Allergies and Infectious Diseases in Bethesda, USA. He briefly returned to Ireland as a lecturer at Dublin City University, before taking Director level roles at the University of Technology Sydney in Australia, and later McGill University, Canada. Returning home in 2013, he became the Professor in Infectious Diseases at Queens University of Belfast, Northern Ireland, and since 2019 has taken the role of Science Foundation Ireland (SFI) Professor in Molecular Parasitology at the National University of Ireland Galway.

The desktop publishing production is very high, with excellent colour figures and well-designed schematics throughout. More importantly, perhaps, each chapter comes with an extensive reference list which, if a back of the envelope calculation allows, likely cites over 2,500 source articles in total. It's very hard to identify then which literature, if any, is missing. Dipping into this alphabetical treasure trove is something I look forward to in years to come. I confidently say in years to come for I have had the first edition of Fasciolosis in my library since 1999. I have used its contents for undergraduate and postgraduate teaching and will now happily include various updates from this second edition.

Both editions of Fasciolosis were expertly edited by Prof John Dalton. It is evidence enough to his academic passion for fluke. Notably, although there is a similar total number of pages in each edition, in the new edition, each chapter is now in two-column format. This change roughly equates to twice the information conveyed, which is justifiable given the last two decades of research. For example, from 2006 onwards, fasciolosis has been rebranded within the WHO's Neglected Tropical Diseases that puts a new spotlight on infection and disease in people across the world.

Indeed, there is much to digest and learn a new from this expanded second edition. I expect John has had to work twice as hard to bring all this together and I am delighted that he has shared his and his co-authors' vision on research on fluke. To close, I strongly recommend this book to all our readers.

Erscheint lt. Verlag 14.12.2021
Verlagsort Oxford
Sprache englisch
Themenwelt Medizin / Pharmazie
Naturwissenschaften Biologie Mikrobiologie / Immunologie
Veterinärmedizin Klinische Fächer Parasitologie
Schlagworte Development • Fasciola gigantica • Fasciola hepatica • Fascioliasis • Fasciolosis • genomics • Glycomics • helminths • human fasciolosis • immunology • liver fluke • Metabolism • Neurobiology • Parasites • Pathology • Proteomics • snail vectors • Transcriptomics • trematodes • vaccines
ISBN-10 1-78924-618-0 / 1789246180
ISBN-13 978-1-78924-618-6 / 9781789246186
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