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Monitoring Neuronal Activity -

Monitoring Neuronal Activity

A Practical Approach

J. A. Stamford (Herausgeber)

Buch | Softcover
320 Seiten
1992
Oxford University Press (Verlag)
978-0-19-963243-5 (ISBN)
CHF 159,15 inkl. MwSt
Although nerve cells generate electrical impulses, the events of neurotransmission also involve ion fluxes, changes in cell metabolism and release of chemical neurotransmitters. The methods in this book describe the different facets of nerve cell activity and the ways in which it may be monitored.
Although most often considered in terms of the generation of action potentials, there are several other electrical, metabolic and ionic correlates of neuronal activity. This book draws together in a single volume, ten different facets of the activity of nerve cells. There are chapters on the monitoring of extracellular unit activity, intracellular voltage and current clamping, patch clamping, video imaging, in vivo voltammetry, intracerebral dialysis, antibody micro- and ion-selective electrodes. The techniques described range from the well-established to the experimental. In each case the chapters include up-to-date information, methodological tips and detailed protocols allowing the reader to follow each method in a stepwise fashion. The wide range of techniques in the book should be of interest to neuroscientists, whether concerned with traditional or novel indices on neuronal function.

Section I: The electrical activity of nerve tissue: J. Millar: Extracellular single and multiple unit recording with microelectrodes; E.M. Silinsky: Intracellular recording methods for neurones; N.B. Standen & P. Stanfield: Patch clamp techniques for single channel and whole cell recording; M.M. Haglung & G.G. Blasdel: Video imaging of neuronal activity using voltage-sensitive dyes; Section II: Neurotransmitter release and metabolism: J.A. Stamford, F. Crespi & C.A. Marsden: In vivo voltammetric methods for monitoring monoamine release and metabolism;T. Sharp & T. Zetterstrom: In vivo measurement of neurotransmitter release and metabolism using brain microdialysis; A.W. Duggan: Preparation, use and analysis of antibody microprobes; Section III: Metabolic and ionic indices of nerve cell activity: L. Sokoloff, C. Kennedy & C.B. Smith: Metabolic mapping of local neuronal activity; M.R. Duchen: Fluorescence-monitoring cellular chemistry in vivo; E. Sykova: Ion selective microelectrodes.

Reihe/Serie Practical Approach Series ; 87
Zusatzinfo colour, halftone, and line illustrations, tables
Verlagsort Oxford
Sprache englisch
Maße 157 x 235 mm
Gewicht 468 g
Themenwelt Studium 1. Studienabschnitt (Vorklinik) Anatomie / Neuroanatomie
Naturwissenschaften Biologie Humanbiologie
Naturwissenschaften Biologie Zoologie
ISBN-10 0-19-963243-X / 019963243X
ISBN-13 978-0-19-963243-5 / 9780199632435
Zustand Neuware
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