Molecular Mechanisms of IgE Regulation

Donata Vercelli, etc. (Autoren)

Buch | Hardcover

258 Seiten

1997
John Wiley & Sons Ltd (Verlag)
978-0-471-97138-2 (ISBN)

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The IgE antibody isotope is responsible for allergic reactions, a problem which affects about 20 per cent of the population. This volume based on research on the molecular mechanisms of IgE regulation. sees the specialist authors take the approach of examining their own work to date.

The IgE antibody isotope is responsible for allergic reactions, a problem which affects about 20 per cent of the population. Thus, an understanding of how, when and why IgE is produced is crucial for the development of appropriate treatments for allergic disorders. This volume based on research on the molecular mechanisms of IgE regulation. sees the authors, specialists in the field, take the approach of examining their own work to date.

The cells and the cytokines; IL-13/IL-4 in atopy; the IL-4 promoter in mast cells and T cells; the chromosome 5/atopy linkage; how T cells direct IgE switching; transcription and switching; local and general regulators of IgE switching; STATs and switching; regulation of human germ-line transcription; switching-5' events; splicing-3' events; CD23; IgE regulation in tissues.

Erscheint lt. Verlag	27.8.1997
Zusatzinfo	Ill.
Verlagsort	Chichester
Sprache	englisch
Maße	156 x 235 mm
Gewicht	500 g
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Dermatologie
Themenwelt	Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
ISBN-10	0-471-97138-3 / 0471971383
ISBN-13	978-0-471-97138-2 / 9780471971382
Zustand	Neuware