Molecular Evolution on Rugged Landscapes
Westview Press Inc (Verlag)
978-0-201-52150-4 (ISBN)
Perelson, Alan S. | Kauffman, Stuart A.
About the Santa Fe Institute -- Santa Fe Institute Editorial Board August 1989 -- Santa Fe Institute Studies in the Sciences of Complexity -- Preface: Applied Molecular Evolution on Rugged Fitness Landscapes -- Rugged Landscapes and Evolution -- Optimization on Rugged Landscapes -- A Spin-Glass Model of Evolution -- What Can Physics Do For Biology? -- Optimization of RNA Structure and Properties -- Somatic Evolution of Antibody Variable-Region Genes & Maturation of the Immune Response -- Affinity Maturation: A Retrospective View -- Maturation through Hypermutation and Selection -- Affinity Maturation on Rugged Landscapes -- Maturation of the Humoral Immune Response: A Neo-Darwinian Process? -- The NK Model of Rugged Fitness Landscapes and Its Application to Maturation of the Immune Response -- Use of Antibodies as Molecular Mimics to Probe Intermolecular Interaction Landscapes -- Affinity Maturation and Learning in Immune Networks -- Auto-Anti-ldiotype and Antigen as Selective Factors Driving B-Cell Affinity Maturation in the Immune System -- Somatic Mutation and the Antibody Repertoire: A Computational Model of Shape Space -- Applied Molecular Evolution -- Evolution of Proteins from Random Sequences: A Model for the Protein Sequence Space and an Experimental Approach -- Studies in the Evolution of Biological Activity from Random Sequences -- The Catalytic Potential of RNA -- Origin of Life Models -- Dynamics of Autocatalytic Reaction Networks
| Sprache | englisch |
|---|---|
| Maße | 152 x 229 mm |
| Gewicht | 453 g |
| Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
| Naturwissenschaften ► Biologie ► Zoologie | |
| ISBN-10 | 0-201-52150-4 / 0201521504 |
| ISBN-13 | 978-0-201-52150-4 / 9780201521504 |
| Zustand | Neuware |
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