Growing Bone

James F. Whitfield (Autor)

Buch | Hardcover

272 Seiten

2007 | 2nd edition
CRC Press (Verlag)
978-1-58706-156-1 (ISBN)

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Growing numbers of men and many more women are suffering from crippling bone loss called osteoporosis. By 2050 50% of Americans over 50 will be at risk of, or actually have, osteoporosis. In this book the reader will meet the newest real and possible bone builders and learn how they might work. These include novel steroids, an osteogenic growth peptide (OGP), leptin from both fat cells and osteoblasts and the many kinds of statin that are widely used to reduce blood cholesterol and seem to prevent Alzheimer’s disease. But the spotlight must be directed onto the currently most promising bone growers, the 84-amino acid parathyroid hormone (PTH) and three of its 31- and 34-amino-acid fragments.

James F. Whitfield, Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada.

Preface, Introduction 1. What Is Osteoporosis? 2. BMUS— The Microcrack Fixers 3. Menopause and Bone Loss 4. The Amazing Bone-Anabolic PTHs 5. How Might PTHs Stimulate Bone Growth? 6. The Clinical Prospects of the Invincible PTHs 7. OGP— The Osteogenic Growth Peptide 8. The Statins 9. Surface Signaling Steroids— Real Anabolics or Pseudo-Anabolics? 10. Strontium, Calcium’s Big Brother 11. Afterword

Erscheint lt. Verlag	16.10.2007
Zusatzinfo	42 Illustrations, black and white
Verlagsort	London
Sprache	englisch
Maße	152 x 229 mm
Gewicht	498 g
Themenwelt	Medizin / Pharmazie ► Allgemeines / Lexika
	Medizinische Fachgebiete ► Chirurgie ► Unfallchirurgie / Orthopädie
	Medizinische Fachgebiete ► Innere Medizin ► Rheumatologie
	Naturwissenschaften ► Biologie
ISBN-10	1-58706-156-2 / 1587061562
ISBN-13	978-1-58706-156-1 / 9781587061561
Zustand	Neuware