Inhibitors of Protein–Protein Interactions (eBook)

Small Molecules, Peptides and Macrocycles

United Kingdom) Tavassoli Ali (University of Southhampton (Herausgeber)

eBook Download: PDF

2020
342 Seiten
Royal Society of Chemistry (Verlag)
978-1-83916-067-7 (ISBN)

Infos

Illustrated throughout with successful case studies, this book provides a holistic, cutting-edge view of the subject area and is ideal for chemical biologists and medicinal chemists interested in developing PPI inhibitors.

Inhalt

Identification of Cellular Protein-protein Interactions; Target-based Screening and Structure-based Design Approaches to Develop Modulators of Protein-protein Interactions; The Challenge of Prosecuting Intracellular Protein-Protein Interactions: A Multi-Modality Examination of Chemical Matter Identification, Biophysical Characterization, and Membrane Permeability; Identifying and Developing Small Molecule Inhibitors of Protein-protein Interactions; Macrocycles as Inhibitors of Protein-Protein Interactions; Genetically-encoded SICLOPPS Libraries for the Identification of PPI Inhibitors; RaPID Discovery of Macrocyclic Peptide Inhibitors of Protein-protein Interactions; Bicyclic Peptide Inhibitors of Protein-Protein Interactions; Stapled Peptide Inhibitors of Protein–Protein Interactions; α-Helix Mimetics as Inhibitors of Protein-Protein Interactions

Produkt-Details

• Erscheint lt. Verlag: 25.11.2020
• Reihe/Serie: ISSN
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie
• Themenwelt: Naturwissenschaften ► Physik / Astronomie ► Angewandte Physik
• ISBN-10: 1-83916-067-5 / 1839160675
• ISBN-13: 978-1-83916-067-7 / 9781839160677