Photoperiodism, Melatonin and the Pineal

Ciba Foundation Symposium (Autor)

Buch | Hardcover

320 Seiten

1985
John Wiley & Sons Ltd (Verlag)
978-0-471-91086-2 (ISBN)

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Photoperiodism, melatonin and the pineal Ciba Foundation Symposium 117 Chairman: R.V. Short 1985 Melatonin was isolated from the mammalian pineal in 1985, but only relatively recently, as the Chairman points out, has evidence accumulated for its role as the Hormone of Darkness, the Hourglass of Time'. The rhythmic melatonin signal from the pineal appears to provide information about photoperiod in many species that show seasonal cycles in reproduction, moulting and other processes. But how do animals respond to the pineal melatonin signal? What determines photoperiodism in birds, which do not seem to use this signal to regulate breeding? What is the significance of retinal melatonin? Does melatonin have a function in humans? These are amongst the issues considered at the symposium recorded in this book. In addition to the morphology and photoneural control of the pineal, the contributors describe the effects of melatonin and of manipulating photoperiod in several laboratory and economically important species - hormones, seasonal cycles, circadian rhythms and influences during development and sexual maturation have been studied.
In humans, the possible significance of melatonin in puberty, malignant disease and affective disorders is considered, as are results suggesting that melatonin can entrain fatigue (or alertness), with discussion of the therapeutic potential of this hormone in certain disturbances of biological rhythm, including jet lag. This book should be of interest to physiologists, neuropharmacologists, endocrinologists, behavioural biologists, psychologists and clinical investigators with a special interest in the pineal. Other Ciba Foundation Symposia published by Pitman: No 102: Origins and development of adaptation Chairman: B.C. Clarke 1984 ISBN 0 272 79749 9 No 104: Photoperiodic regulation of insect and molluscan hormones Chairman: W. Mordue 1984 ISBN 0 272 79751 0 No 113: Retinoids, differentiation and disease Chairman: M.B. Sporn 1985 ISBN 0 272 79813 4

Symposium on Melatonin and the pineal, held at the Ciba Foundation, London, 5 7 March 1985 The subject of this symposium was proposed by Professor V. Marks and Dr J. Arendt Editors: David Evered (Organizer) and Sarah Clark R. V. Short Photoperiodism, melatonin and the pineal: it's only a question of time L. Vollrath Mammalian pinealocytes: ultrastructural aspects and innervation Discussion M. C. Moore-Ede and M. L. Moline Circadian rhythms and photoperiodism Discussion D. C. Klein Photoneural regulation of the mammalian pineal gland Discussion M. H. Hastings, J. Herbert, N. D. Martensz and A. C. Roberts Melatonin and the brain in photoperiodic mammals Discussion M. Menaker Eyes - the second (and third) pineal glands? Discussion B. K. Follett, R. G. Foster and T. J. Nicholls Photoperiodism in birds Discussion General discussion I Local and cellular actions of melatonin 106 Retinal rhythms 107 Light sensitivity and melatonin synthesis S. M. Reppert, M. J. Duncan and B. D. Goldman Photic influences on the developing mammal Discussion G. A. Lincoln, F. J. P. Ebling and O. F. X. Almelda Generation of melatonin rhythms Discussion E. L. Bittman The role of rhythms in the response to melatonin Discussion L. Martinet and D. Allain Role of the pineal gland in the photoperiodic control of reproductive and non-reproductive functions in mink (Mustela vison) Discussion S. M. Armstrong and J. Redman Melatonin administration: effects on rodent circadian rhythms Discussion P. C. Sizonenko, U. Lang, R. W. Rivest and M. L. Aubert The pineal and pubertal development Discussion A. J. Lewy, R. L. Sack and C. M. Singer Melatonin, light and chronobiological disorders Discussion L. Wetterberg Melatonin and affective disorders Discussion J. Arendt, C. Bojkowski, S. Folkard, C. Franey, V. Marks, D. Minors, J. Waterhouse, R. A. Wever, C. Wildgruber and J. Wright Some effects of melatonin and the control of its secretion in humans Discussion L. Tamarkin, O. F. X. Almeida and D. N. Danforth Jr Melatonin and malignant disease Discussion General discussion II Melatonin assay technology 300 How important is the duration of the melatonin signal? Index of contributors Subject index

Erscheint lt. Verlag	12.3.1985
Reihe/Serie	Ciba Foundation Symposium ; No. 117
Verlagsort	Chichester
Sprache	englisch
Maße	177 x 277 mm
Gewicht	584 g
Themenwelt	Medizinische Fachgebiete ► Innere Medizin ► Endokrinologie
Themenwelt	Naturwissenschaften ► Biologie ► Zoologie
ISBN-10	0-471-91086-4 / 0471910864
ISBN-13	978-0-471-91086-2 / 9780471910862
Zustand	Neuware