The Design of Covalent-Based Inhibitors
Academic Press Inc (Verlag)
978-0-12-821689-7 (ISBN)
Richard A. Ward is at AstraZeneca, UK Neil Grimster is at AstraZeneca, USA
Preface Richard Andrew Ward and Neil Grimster 1. The history of covalent inhibitors Renato A. Bauer 2. Kinetic Mechanisms of Covalent Inhibition Claire Louise McWhirter 3. Covalent Drugs in Development for Immune-Mediated Diseases Leonard Sung 4. Chemistry Perspectives of Reversible Covalent Drugs Jianmin Gao 5. Design of Next-Generation Covalent Inhibitors: Targeting Residues Beyond Cysteine Lyn Jones 6. Boron and Covalent Inhibition Andrew Leach 7. Measuring and predicting warhead and residue reactivity Christopher Rowley 8. Computational Support of Structure-based Targeted Covalent Inhibitor Design Robert Abel 9. Novel approaches to covalent inhibition Nir London 10. The future of covalent inhibition Gyorgy M. Keseru
| Erscheinungsdatum | 16.07.2021 |
|---|---|
| Reihe/Serie | Annual Reports in Medicinal Chemistry |
| Verlagsort | San Diego |
| Sprache | englisch |
| Maße | 152 x 229 mm |
| Gewicht | 610 g |
| Themenwelt | Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie |
| Naturwissenschaften ► Chemie | |
| ISBN-10 | 0-12-821689-1 / 0128216891 |
| ISBN-13 | 978-0-12-821689-7 / 9780128216897 |
| Zustand | Neuware |
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