Advances in Hydrogen Sulfide Biology

Buch | Hardcover

236 Seiten

2021 | 1st ed. 2021
Springer Verlag, Singapore
978-981-16-0990-9 (ISBN)

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Hydrogen sulfide (H2S) has emerged as an important gas signalling molecule in a series of organs/tissues, on the diseases of which it plays protective roles, such as proangiogenic effects in ischemic tissues, antiapoptotic effects in the cardiomyocytes, regularization of fatal arrhythmia in myocardial infarction, amelioration of inflammation in autoimmune diseases, modification of neuronal transmission, increase in sodium excretion from the kidney, and amelioration of insulin resistance, etc. This book focuses on the effect of hydrogen sulfide in cardiovascular system, immune system, nervous system, kidney, as well as on the metabolism of glucose and lipids and regulation of ion channels and so on. This book also provides the advances in the understanding of endogenous H2S metabolism and H2S protein targets, as well as H2S donors. It will benefit researchers in both academics and industry working on the underlying mechanism of H2S field and the future of translational medicine of H2S.

Yi-Chun Zhu MD, Ph.D., Chang Jiang Professor, Department of Physiology and Pathophysiology, Shanghai Medical School, Fudan University

Introduction.- Metabolism of endogenous H2S and its metabolites.- A common molecular switch for H2S to regulate multiple protein targets.- The protective role of H2S in the heart.- The proangiogenic effects of H2S.- H2S and the immune system.- Protection of H2S on the neurons.- The role of H2S in the metabolism of glucose and lipids.- Regulation of the ion channels by H2S.- The epigenetic mechanisms for H2S signalling.- The development of H2S donor.

Erscheinungsdatum	30.07.2021
Reihe/Serie	Advances in Experimental Medicine and Biology ; 1315
Zusatzinfo	39 Illustrations, color; 8 Illustrations, black and white; IX, 236 p. 47 illus., 39 illus. in color.
Verlagsort	Singapore
Sprache	englisch
Maße	178 x 254 mm
Themenwelt	Medizin / Pharmazie ► Medizinische Fachgebiete ► Pharmakologie / Pharmakotherapie
	Medizin / Pharmazie ► Studium
	Naturwissenschaften ► Biologie
Schlagworte	cardiovascular protection • drug discovery • epigenetics • Hydrogen sulfide • Molecular Switch • Translational Medicine
ISBN-10	981-16-0990-X / 981160990X
ISBN-13	978-981-16-0990-9 / 9789811609909
Zustand	Neuware