The Discovery and Utility of Chemical Probes in Target Discovery (eBook)

UK) Brennan Paul (University of Oxford, UK) Rodriguez Saleta Vazquez (University of Oxford (Herausgeber)

eBook Download: EPUB

2020
326 Seiten
Royal Society of Chemistry (Verlag)
978-1-83916-084-4 (ISBN)

Infos

Ideal for students and established biochemists, this book will cover new technologies for probe discovery, new probe modalities, the new field of probes for RNA targets and the mature field of kinase chemical probes.

Inhalt

Introduction to Chemical Probes; DNA-Encoded Chemistry and its use to Discover Chemical Probes; Computational Methods for the Discovery of Chemical Probes; Best Practices for Design and Characterization of Covalent Chemical Probes; Cyclic Peptides as Chemical Probes; Discovery and Use of Natural Products and Derivatives as Chemical Probes; Targeted Protein Degradation Chemical Probes; Chemical Probes for Kinases; Chemical Probes to Control RNA Function; Assays to Characterize Cellular Pharmacology of a Chemical Probe; Chemical Probes in Cellular Assays for Target Validation and Screening in Neurodegeneration

Produkt-Details

• Erscheint lt. Verlag: 17.11.2020
• Reihe/Serie: Chemical Biology
• Reihe/Serie: ISSN
• Reihe/Serie: ISSN
• Reihe/Serie: ISSN
• Sprache: englisch
• Themenwelt: Naturwissenschaften ► Biologie ► Biochemie
• Themenwelt: Naturwissenschaften ► Chemie ► Organische Chemie
• Schlagworte: Akane • Ana • barril • brennan • Bridget • Brown • Chemical • da • Daniel • DI • Ding • Discovery • Elena • Gennady • Haggarty • Huber • J • Kawamura • KE • Keefe • Khanna • Kilian • Kira • Kita • London • Masaki • May • NIR • Paul • poda • Probes • rodriguez • Saleta • Silva • Stephen • target • Tom • Tony • Utility • vazquez • Wagner • Weissman • xavier
• ISBN-10: 1-83916-084-5 / 1839160845
• ISBN-13: 978-1-83916-084-4 / 9781839160844