The Oxford Handbook of Neuronal Protein Synthesis
Oxford University Press Inc (Verlag)
978-0-19-068630-7 (ISBN)
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Dr. Sossin received undergraduate degrees in Biology and Computer Science from MIT in 1984 and completed his PhD at Stanford in Biological Sciences with Dr. Richard Scheller in 1989. He did post-doctoral work with Dr. Schwartz at Columbia Univeristy in the Center for Neurobiology and Behavior before being appointed Assistant Professor at the Montreal Neurological Institute at McGill University in 1993 where he is now a James McGill Professor. He has been an EJLB Scholar, CIHR investigator and FRSQ Checheur Nationaux. Dr. Sossin has published over 125 papers on the molecular and cellular processes underlying memory formation and maintenance with a particular interest in the role of persistent protein kinases and the regulation of local translation in this process.
Part I: Role of Translation Factors
1. Regulation of Protein Synthesis by eIF4E in the Brain
Kleanthi Chalkiadaki, Stella Kouloulia, Clive R. Bramham, and Christos G. Gkogkas
2. Translational Control Through the eIF4E Binding Proteins in the Brain
Argel Aguilar-Valles, Edna Matta-Camacho, and Nahum Sonenberg
3. The Integrated Stress Response in Memory and Cognitive Disorders
Jacqunae L. Mays and Mauro Costa-Mattioli
4. The Role of the Eukaryotic Elongation Factor 2 (eEF2) Pathway in Neuronal Function
Elham Taha and Kobi Rosenblum
5. Sidekick No More: Neural Translation Control by p70 ribosomal S6 kinase 1
Aditi Bhattacharya
Part II: Role of Specific Elements in the mRNA
6. Dendritic Targeting and Regulatory RNA Control of Local Neuronal Translation
Taesun Eom, Ilham A. Muslimov, Anna Iacoangeli, and Henri Tiedge
7. Internal Ribosome Entry Site-Mediated Translation in Neuronal Protein Synthesis
Martin Holcik
8. RNA Modifications in the Central Nervous System
Dan Ohtan Wang
9. Role of CPEB-Family Proteins in Memory
Kausik Si
10. FMRP and MicroRNAs in Neuronal Protein Synthesis
Monica C. Lannom and Stephanie Ceman
11. Focusing on mRNA Granules and Stalled Polysomes Amidst Diverse Mechanisms Underlying mRNA Transport, mRNA Storage and Local Translation
Mina N. Anadolu and Wayne S. Sossin
Part III: Physiological Roles of Translation
12. Protein Synthesis and Synapse Specificity in Functional Plasticity
Radha Raghuraman, Amrita Benoy, and Sreedharan Sajikumar
13. Regulation of Synaptic Homeostasis by Translational Mechanisms
Megumi Mori, Jay Penney, and Pejmun Haghighi
14. Multiple Roles of RNA Regulatory Factors in Neuronal Development and Function in C. elegans
Matthew G. Andrusiak and Yishi Jin
15. Regulation of mRNA Translation in Axons
Priyanka Patel, Pabitra K. Sahoo, Amar N. Kar, and Jeffery L. Twiss
16. Protein Synthesis and Translational Control in Neural Stem Cell Development and Neurogenesis
Lamees Mohammad, Joscelyn Wiseman, Sarah Erickson, and Guang Yang
Part IV: Neuronal Protein Synthesis and Disease
17. Translational Controls in Pain
Sarah Loerch, June Bryan De La Peña, Jane Song, Joseph J. Pancrazio, Theodore J. Price, and Zachary T. Campbell
18. Dysregulated Translation in Autism Spectrum Disorder
Emanuela Santini and Anders Borgkvist
19. Neuronal mRNA Translation in Addiction
Emma Puighermanal and Emmanuel Valjent
20. Dysregulated Protein Synthesis in Major Depression Disorder
Chelcie F. Heaney and Kimberly F. Raab-Graham
21. Dysregulation of Neuronal Protein Synthesis in Alzheimer's Disease
Tao Ma
22. RNA-Binding Proteins and Translation in Neurodegenerative Disease
Kent E. Duncan
23. Role of Eukaryotic Initiation Factor eIF2B in Vanishing White Matter Disease
Truus E. M. Abbink, Lisanne E. Wisse, Xuemin Wang, and Christopher G. Proud
Index
Erscheinungsdatum | 19.04.2021 |
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Reihe/Serie | Oxford Handbooks |
Verlagsort | New York |
Sprache | englisch |
Maße | 249 x 175 mm |
Gewicht | 1451 g |
Themenwelt | Naturwissenschaften ► Biologie ► Genetik / Molekularbiologie |
Naturwissenschaften ► Biologie ► Humanbiologie | |
Naturwissenschaften ► Biologie ► Zellbiologie | |
Naturwissenschaften ► Biologie ► Zoologie | |
ISBN-10 | 0-19-068630-8 / 0190686308 |
ISBN-13 | 978-0-19-068630-7 / 9780190686307 |
Zustand | Neuware |
Informationen gemäß Produktsicherheitsverordnung (GPSR) | |
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