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Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry -

Wilson and Gisvold's Textbook of Organic Medicinal and Pharmaceutical Chemistry

Buch | Hardcover
1000 Seiten
2003 | 11th Revised edition
Lippincott Williams and Wilkins (Verlag)
978-0-7817-3481-3 (ISBN)
CHF 83,80 inkl. MwSt
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Covers the principles of chemistry, biochemistry, and biology that underlie the field of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of pharmaceutical agents. This book serves the needs of graduate, undergraduate pharmacy and chemistry students.
For over half a century, this book has served the discipline of medicinal chemistry for both graduate and undergraduate pharmacy and chemistry students as well as practicing pharmacists. Fully updated for the Eleventh Edition, coverage begins with the fundamental principles of chemistry, biochemistry, and biology that underlie the discipline of medicinal chemistry. These principles are then applied to understanding the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. The subject matter is organized by pharmaceutical and therapeutic classes, providing a bridge between the basic sciences and clinical practice. The text contains many tables for quick reference to names, formulations, dosages, and applications

Chapter 1. Introduction John H. Block and John M. Beale, Jr. Chapter 2. Physicochemical Properties in Relation to Biological Action John H. Block Chapter 3. Combinatorial Chemistry Douglas R. Henry Chapter 4. Metabolic Changes of Drugs and Related Organic Compounds Stephen J. Cutler and John H. Block Chapter 5. Prodrugs and Drug Latentiation Forrest T. Smith and C. Randall Clark Chapter 6. Biotechnology and Drug Discovery John M. Beale, Jr. Chapter 7. Immunobiologicals John M. Beale, Jr. Chapter 8. Anti-Infective Agents John M. Beale, Jr. Chapter 9. Antimalarials John H. Block Chapter 10. Antibacterial Antibiotics John M. Beale, Jr. Chapter 11. Antiviral Agents John M. Beale, Jr. Chapter 12. Antineoplastic Agents William A. Remers Chapter 13. Agents for Diagnostic Imaging Jack N. Hall, Tim B. Hunter, and T. Kent Walsh Chapter 14. Central Nervous System Depressants Eugene I. Isaacson Chapter 15. Central Nervous System Stimulants Eugene I. Isaacson Chapter 16. Adrenergic Agents Rodney L. Johnson Chapter 17. Cholinergic Drugs and Related Agents George H. Cocolas and Steven J. Cutler Chapter 18. Diuretics Daniel A. Koechel Chapter 19. Cardiovascular Agents Steven J. Cutler and George H. Cocolas Chapter 20. Local Anesthetic Agents Gareth Thomas Chapter 21. Histamine and Antihistaminic Agents Thomas N. Riley and Jack DeRuiter Chapter 22. Analgesic Agents Robert E. Willette Chapter 23. Steroids and Therapeutically Related Compounds Philip J. Proteau Chapter 24. Prostaglandins, Leukotrienes, and Other Eicosanoids Thomas J. Holmes, Jr. Chapter 25. Proteins, Enzymes, and Peptide Hormones Stephen J. Cutler and Horace G. Cutler Chapter 26. Vitamins and Related Compounds Michael J. Deimling, Gustavo R. Ortega, and Jaime N. Delgado Chapter 27. An Introduction to the Medicinal Chemistry of Herbs John M. Beale, Jr. Chapter 28. Computational Chemistry and Computer-Assisted Drug Design J. Phillip Bowen Appendix. Calculated Log P, Log D, and pKa Index

Erscheint lt. Verlag 1.1.2004
Überarbeitung Jaime N. Delgado
Zusatzinfo 1125
Verlagsort Philadelphia
Sprache englisch
Maße 216 x 280 mm
Gewicht 2061 g
Themenwelt Medizin / Pharmazie Medizinische Fachgebiete Pharmakologie / Pharmakotherapie
Naturwissenschaften Chemie
ISBN-10 0-7817-3481-9 / 0781734819
ISBN-13 978-0-7817-3481-3 / 9780781734813
Zustand Neuware
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