In-Cell NMR Spectroscopy

Biomolecular Structure and Function

Alexander Shekhtman, David S. Burz (Herausgeber)

Buch | Softcover

152 Seiten

2020
MDPI (Verlag)
978-3-03928-254-8 (ISBN)

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This Special Issue examines state-of-the-art in-cell NMR spectroscopy as it relates to biological systems of increasing complexity. The compendia of research and recent innovations from prominent laboratories in the field of solid state and solution in-cell NMR spectroscopy, metabolomics and technology development are presented. The work establishes in-cell NMR spectroscopy as the premier method for determining the structures and interaction capabilities of biological molecules at high resolution within the delicately intricate interior of living cells, and the means of utilizing cells as living laboratories to directly assess the effects of exogenous and endogenous stimuli on cell physiology.]

Erscheinungsdatum	16.05.2020
Verlagsort	Basel
Sprache	englisch
Maße	170 x 244 mm
Themenwelt	Naturwissenschaften ► Biologie ► Allgemeines / Lexika
Schlagworte	2D INADEQUATE • Adenylate kinase • antimicrobial peptide • cross-correlated relaxation • crystalline and amorphous starch • dihydrofolate reductase • DNA • DNP • drug discovery • Enzyme activity • Enzyme kinetics • In-Cell NMR • in-situ NMR • intrinsically disordered proteins • lipid membrane • live cell • magic-angle spinning • Mammalian Cells • MARK2 phosphorylation • mRNA • NMR spectroscopy • non-uniform sampling 2 • paramagnetic effects • Post-translational modifications • Protein dynamics • Protein Interactions • Protein modification • protein NMR • Protein Structure • protein structure determination 1 • protein structure-function • Review • Ribosome • rRNA • Solid-State NMR • spectrum reconstruction 3 • structural calculation 4 • Structure Function • target engagement • Tau • thioredoxin • Thymidylate synthase • time-resolved NMR • whole cell NMR
ISBN-10	3-03928-254-9 / 3039282549
ISBN-13	978-3-03928-254-8 / 9783039282548
Zustand	Neuware