Characterization of Neural Activity Using Complex Network Theory
An Application to the Study of Schizophrenia
Seiten
2020
|
1st ed. 2021
Springer International Publishing (Verlag)
978-3-030-49899-3 (ISBN)
Springer International Publishing (Verlag)
978-3-030-49899-3 (ISBN)
This book reports on the development and assessment of a novel framework for studying neural interactions (the connectome) and their dynamics (the chronnectome). Using EEG recordings taken during an auditory oddball task performed by 48 patients with schizophrenia and 87 healthy controls, and applying local and network measures, changes in brain activation from pre-stimulus to cognitive response were assessed, and significant differences were observed between the patients and controls. This book investigates the source of the network abnormalities and presents new evidence for the disconnection hypothesis and the aberrant salience hypothesis with regard to schizophrenia. Moreover, it puts forward a novel approach to combining local regularity measures and graph measures in order to characterize schizophrenia brain dynamics, and presents interesting findings on the regularity of brain patterns in healthy control subjects versus patients with schizophrenia. Besides providing new evidence for the disconnection hypothesis, it offers a source of inspiration for future research directions in the field.
Introduction.- Hypotheses and objectives.- 3 Materials and methods.- Results.- Discussion
| Erscheinungsdatum | 06.07.2020 |
|---|---|
| Reihe/Serie | Springer Theses |
| Zusatzinfo | XVIII, 67 p. 24 illus., 19 illus. in color. |
| Verlagsort | Cham |
| Sprache | englisch |
| Maße | 155 x 235 mm |
| Gewicht | 307 g |
| Themenwelt | Mathematik / Informatik ► Informatik ► Theorie / Studium |
| Mathematik / Informatik ► Mathematik ► Angewandte Mathematik | |
| Mathematik / Informatik ► Mathematik ► Graphentheorie | |
| Naturwissenschaften ► Biologie ► Humanbiologie | |
| Technik | |
| Schlagworte | Aberrant Salience in Schizophrenia • Brain Complexity • Evidence for Disconnection Hypothesis • Evoked Response • Neural Coupling • Neural Dynamics in Schizophrenia • neural network modeling • neural pathways • neural synchronization • Schizophrenia Heterogeneity • Schizophrenia Subgroups • Schizophrenia Underpinnings • spectral entropy • Task-related Activity • Time-frequency Assessment • wavelet entropy |
| ISBN-10 | 3-030-49899-9 / 3030498999 |
| ISBN-13 | 978-3-030-49899-3 / 9783030498993 |
| Zustand | Neuware |
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